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Virolex (Acyclovir)
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Acyclovir

Virolex is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein-Barr virus infection. It can be taken by mouth, applied as a cream, or injected.Common side effects include nausea and diarrhea. Potentially serious side effects include kidney problems and low platelets. Greater care is recommended in those with poor liver or kidney function. It is generally considered safe for use in pregnancy with no harm having been observed. It appears to be safe during breastfeeding. Virolex is a nucleoside analogue that mimics guanosine. It works by decreasing the production of the virus's DNA.Virolex was patented in 1974, and approved for medical use in 1981. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. It is available as a generic medication and is marketed under many brand names worldwide. The wholesale cost as of 2014 to 2016 was between US$0.03 and US$0.12 for a typical dose by mouth. The cost of a typical course of treatment in the United States is less than US$25. In 2016 it was the 195th most prescribed medication in the United States with more than 3 million prescriptions.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Regional activity of enkephalin- and angiotensin II-forming peptidases in the rat brain and other peripheral tissues with different craving for ethanol Immunohistochemical score (IHS) was calculated as the product of SI and SP. Estimation of the measurement uncertainty by the bottom-up approach for the determination of methamphetamine and amphetamine in urine.

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From both group subjects, 10 mL of blood sample was drawn by puncturing the antecubital vein, and PbB, serum LP, RBC-SOD, RBC-CAT, plasma CP, and serum nitrite were estimated using standard methods. In the current study, this element, termed Tn5281, was shown to relocate in the absence of homologous recombination in E. As the original in vivo Draize eye test has been criticized for limited predictivity, costs and ethical issues, several animal-free test methods have been developed to categorize substances according to the global harmonized system (GHS) for eye irritation.This review summarizes the progress of alternative test methods for the assessment of eye irritation.

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The expression of P-glycoprotein (Pgp), the protein product of multidrug resistance 1 (MDR1), was investigated with immunocytochemistry and image analysis. To assess the clinical characteristics and course of patients with mild cognitive impairment (MCI) and mild Alzheimer disease (AD) treated with cholinesterase inhibitors (ChEIs) and memantine hydrochloride. Similar complications were evident in nine series published between 1990 and 2012. In clinical medicine, TFF is primarily applied as drugs in the mucosal protection, in the prevention and the treatment of mucosal damage-related diseases and as pathological biomarkers of tumors. Clinical trials demonstrate that both the dihydropyridine calcium channel blocker amlodipine and angiotensin II receptor blockers are effective agents for the management of hypertension in individuals with or without cardiovascular disease.

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Compounds were isolated from the aqueous extract of the leaves of Crataegus pinnatifida var. Gene targeting studies show that, in the knockout mice of steroid 5alpha-reductase type 1 gene, prostaglandin F2alpha receptor gene and cytosolic phospholipase A2 gene, parturition was severely disturbed, although live offspring were delivered by Caesarean section. Anterior cervical diskectomy and fusion in a community hospital setting.

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Tandutinib inhibits FMS receptor signalling, and macrophage and osteoclast formation in vitro. The genetic polymorphisms of DNA repair enzymes,OGG1 Ser326Cys, MUTYH Gln324His, APEX1 Asp148Glu and XRCC1 Arg399Gln, were examined using PCR-RFLP. The effect of PMA on the cAMP response was not influenced by the addition of a phosphodiesterase inhibitor. Our patients remind us that the presence of antisynthetase antibodies (and even antisynthetase syndrome) in a patient with inflammatory myositis does not preclude the diagnosis of cancer-associated myositis.

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Nodes were positive for metastasis in two patients with alveolar rhabdomyosarcoma and undifferentiated sarcoma. circulating ANGPTL3 and ANGPTL4 expression was estimated by real-time polymerase chain reaction (RT-PCR). We used a nationally representative resource to estimate the number of visits to emergency departments (EDs), analyze burn types and demographic patterns, and identify specific consumer products involved.

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Here we demonstrated a successful multiplex assay for quantitative measurement of miRNA21, miRNA222, miRNA20a, and miRNA223, which are associated with nonsmall cell lung cancer. Rigorous and consistent use of treatments is key to relieving symptoms, but many parents experience significant barriers to application.

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Cdc13 enriched along the spindle disappears first, followed by decay of the nuclear signal, whereas Cut2 in the nucleus disappears first, followed by decline in the spindle signal during metaphase-anaphase progression. Modern contraceptive use among young married women has showed a remarkable increase over the last decade in Ethiopia. The use of nanotechnology in agriculture sector will reduce the indiscriminate use of agrochemicals and thus will reduce the load of chemical pollutant. Thereafter, age, body mass index, aortic calcification index (ACI), renal function, serum uric acid concentrations, and comorbidities (diabetes, hypertension, or cardiovascular disease) were compared between the Non-stone and Stone groups.

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To investigate how DA transport is regulated in intact tissue and to examine how amphetamine affects the DAT, the kinetics of DA uptake by the DAT were examined in tissue slices of the mouse caudate-putamen with fast-scan cyclic voltammetry. The NIR fs pulses generate low thermal impact while allowing high penetration depths into tissue. Social environments experienced at different developmental stages profoundly shape adult behavioural and neural phenotypes, and may have important interactive effects. Motor evoked potential (MEP) monitoring has been widely used in brain or spine surgery to recognize potential damage of the pyramidal motor system.

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A comprehensive literature search was conducted for peer-reviewed manuscripts including data around corneal staining, and the results from this search synthesized. Optimization of the experimental set-up is detailed including collimator options and detector operating parameters. Postoperative complications and severe outcome in patients with gallstone disease are associated with a significant increase in LPO level in serum before reoperation. Cycloamidination of Aminoalkenes with Nitriles: Synthesis of Substituted 2-Imidazolines and Tetrahydropyrimidines.

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These included four classes of presumably neutral nuclear loci (allozymes, codominant random amplified polymorphic DNAs (RAPDs), microsatellites, and dominant RAPDs), a class comprising two linked protein-coding nuclear loci under selection, and a marker of the mitochondrial DNA (mtDNA). Lesions, significant for diagnosis and disease stage, with metabolic activity on PET-CT and presumed appropriate for percutaneous approach under US guidance were selected for cytologic aspiration or tissue core biopsies. Selectivity of the passive sampler in river water was demonstrated and the extraction process was independent of sample concentration, even at lower concentration levels of analytes. An AcMNPV recombinant, having wild-type early and late GP64 synthesis, was compared with one in which only late GP64 synthesis occurred. The HRS2 patients were identified from our electronic transplant database, and matched with controls for the following variables: age, sex, etiology, diabetes mellitus, and year of transplant.

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This is a qualitative research based on the sociological phenomenology of Alfred Schutz. This study does not provide evidence for an increased risk of adverse pregnancy outcome after average drug exposure during pregnancy.

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In vivo microscopic analysis of both the corneal epithelial layer cytopathology and the cytology of inflammatory infiltration provides a fast and specific differentiation of keratitis aetiology that may increase the accuracy in the selection of the initial treatment. The caspase-8 homologous cellular FLICE-like inhibitory protein (cFLIP) can also be recruited to the DISC.

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Pancreatic neuroendocrine carcinoma diagnosed using endoscopic ultrasound-guided fine needle aspiration: A case report and literature review. Invasive disease can follow bacteremia causing meningoencephalitis, endocarditis and spontaneous miscarriages in immunocompromised patients and pregnant women respectively.

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Community ambulation in patients with chronic stroke: how is it related to gait speed? We analyse current knowledge of the impact of direct price-cap regulation of generic drugs and the implementation of systems regulating the reimbursement rate, particularly through reference pricing and similar tools, on dynamic price competition between generic competitors in Europe. Recent discoveries have shed new light on the involvement of a class of non-coding RNAs known as microRNAs (miRNA), in keloid formation.

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2-alkynylaryl isocyanates reacted with bis(pinacolato)diboron in the presence of a cationic rhodium(I) catalyst to produce borylated 3-alkylideneoxindoles stereoselectively. In this case report, the authors describe a 51-year-old woman with ARDS, whose HO developed after long-term sedation with neuromuscular blockade agents. The positively chirped broadband IR pulse is suitable for generating a negatively chirped deep-UV pulse, which can be compressed by normal group-velocity dispersion in a transparent medium.

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There are three main approaches namely analytical, cognitive and biological to manage conversion disorder. Effect of the D-Phe2 residue on molecular conformation of an endogenous neuropeptide achatin-I. Clinical signs of Lyme borreliosis in horses include: chronic weight loss, sporadic lameness, laminitis, low grade fever, swollen joints, muscle tenderness, and anterior uveitis. This work demonstrates that Rho kinase inhibition augments neurite elongation in the presence of contact with a PNS-like substrate. We present a novel and easy method of placing these anchoring stitches with good exposure of the subvalvular tissue.

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Comparison of loudspeakers is a major concern during design or product selection. Health inequalities: new concerns about the children of single mothers. Poly(ADP-ribose) polymerase 1 (PARP-1) activity is detected in both neuronal and nonneuronal cells in the CNS, and excessive PARP-1 activity is known to be detrimental to tissue because of the cellular energy loss.

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MR imaging allows precise evaluation of ligaments, muscles, and pelvic organs and provides accurate information for appropriate surgical treatment. Six remote Aboriginal communities and three homelands on the Anangu Pitjantjatjara Lands in the far north-west of South Australia, 1996-1998. Rewarding reviewers, tracking our authors and selective electronic publication. The primary factor necessary for achievement of S(N)Ar reactions is the presence of a good leaving group, which allows facile rearomatization of the ring undergoing nucleophilic attack.

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We sought to assess the presence of lymphatics within the colonic lamina propria in neoplastic and inflammatory conditions using the lymphatic endothelium-specific immunohistochemical marker D2-40. We characterize the optimal set of allocation decisions that maximizes fitness. The dimerization of dSU(VAR)3-9 and the subsequent increase of its methyltransferase activity provide a starting point to understand the molecular details of the formation of heterochromatic structures in vivo.

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Application of 3D printing and computer-assisted surgical simulation in preoperative planning for acetabular fracture A significant correlation was found between the acetabular criteria and age, and between the acetabular criteria and the Lovejoy criteria of the auricular surface. We report case series of 3 cases of neglected dislocations of elbow.

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TOCs were low across the basin and were positively correlated with grain size. Nutrient composition is a poor determinant of the glycaemic response. The amounts of catalytic Fe(II) were higher in ectopic endometrial stromal cells (ecESCs) than in normal eutopic endometrial stromal cells (n-euESCs) both in the tissues and in the corresponding immortalized ESCs. Guidelines for the use of aides in occupational therapy practice.

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Negative self-statements (NST) are used to induce negative mood. In the presence of HRA, both CPY3401 and HPT73 colonized the stomachs of nude mice. Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia. We did not observe any statistically significant circulatory effects or changes in indocyanine green kinetics in liver transplant recipients in the immediate OLT postoperative period caused by short-term mechanical hyperventilation.

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Nursing handovers as resilient points of care: linking handover strategies to treatment errors in the patient care in the following shift. Here we present the histological technique for preparing paraffin-embedded and frozen sections of Drosophila thoracic muscles. Enhancement of slow wave sleep parallel to the satiating effect of acidic fibroblast growth factor in rats.

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Maternal risk factors for abnormal placental growth: the national collaborative perinatal project. Original method for extraction of multiple emboli from segmental branches of pulmonary artery under the conditions of the artificial circulation is described. However, the temporal development and dose-dependence of these TCDD effects on antral hormone levels were quite different than those for hypergastrinemia. A better understanding of the fundamental mechanisms that govern the complex processes of mitochondrial apoptosis is expected to open new perspectives for cancer drug development.

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Severe acute respiratory syndrome: What have we learned two years later? The function of money in relation to self, to others and at the institution Using immunogold electron microscopy, we localized plectin at three prominent sites: 1) Plectin is found at regularly spaced intervals along the cytoplasmic face of the plasma membrane.

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Building materials for animal facilities should be selected to facilitate efficient and hygienic operation. Therefore, we introduce a model of NoN to shape the pattern of brain activations to form a modular environment that is robust. This has to be balanced against that analyzing data emerging from microarrays involves several consecutive steps, and each of them is a potential source of errors.

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Betaxolol versus carvedilol in chronic heart failure (BETACAR study). The observation that trimethylbismuth ((CH(3))(3)Bi), the main volatile derivative of bismuth produced in human feces, inhibited growing cultures of Bacteroides thetaiotaomicron, a representative member of the human physiological gut flora, suggests that these volatiles exert their toxic effects on human health not only by direct interaction with host cells but also by disturbing the physiological gut microflora.

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A comparison of isotope penile blood flow and colour Doppler ultrasonography in the assessment of erectile dysfunction. Evidence suggests that therapy with a calcium channel blocker and an inhibitor of the renin-angiotensin system is one effective strategy for lowering blood pressure and improving outcomes in these populations. We conclude that all three versions of the GDS can be used for screening on depression among NH-patients. These areas broadly coincide with known spawning locations from the period 1940 to 1970.

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We examined whether retired factory workers exposed to any of the 4 dusts of silica, cement, coal and asbestos had more depressive symptoms and anxiety in southern China, which has experienced rapid economic development. The calculations suggest several reactions involving intermediates and Raman scattering experiments confirming the formation of the dimer (ZnC2H5)2. Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery.

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Most felt that MBDS cooperation helped drive and thus added value to their efforts. Differential characteristics of pediatric sinusitis in patients who underwent endoscopic sinus surgery: children vs. Comparison of the toxicity using body residues of DDE and select PCB congeners to the midge, Chironomus riparius, in partial-life cycle tests. Effects of various alcohols applied in vitro on human lymphocyte subtypes and mitogenesis. Before initiating any medical procedure that requires the use of classic laryngoscopy, a thorough and detailed pre-aesthetic evaluation of the dental status of the patient is imperative, in order to identify teeth at risk, analyze the presence of factors associated with difficult intubation and outline a prevention strategy that is tailored to the risk of dental injury of each patient.

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Conditional forebrain deletion of the L-type calcium channel Ca V 1.2 disrupts remote spatial memories in mice. At birth, the internal lingual muscle is therefore reduced in size.

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In both groups, serologic analysis of viral agents (HSV1, HSV2, Herpes zoster, EBV, CMV, adenovirus, influenza, and parainfluenza virus) was performed. Effect of Yersinia pseudotuberculosis pVM82 on the activity of components of complement and phagocytosis by human blood neutrophils To evaluate the contribution of nuclear context to silencing, we developed methodology to isolate silent chromatin for analysis in vitro.

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Hemorrhagic tuberculous pericardial effusions are uncommon and may likely reflect a low incidence of cardiac tuberculosis in community hospitals in the United States. The data suggests that nicotine-induced mitogenic response in AR42J cells closely identifies the response induced by an oxidative biomarker.

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A total of 300 surveys were distributed, 150 of which were returned with complete information for data analysis. Those who had been homeless five years or more reported high rates of alcohol abuse (34.5 percent), illegal drug use (24.1 percent), and psychiatric hospitalization (20.7 percent). Predictive and prognostic biomarkers for targeted therapy in metastatic colorectal cancer.

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Thus, the identification of multiple genes encoding proteins similar to vertebrate nAChR subunits implicates a remarkable heterogeneity for these receptors. A series of genomic clones containing DNA that encodes the chicken gamma-aminobutyric acidA (GABAA) receptor beta 4 subunit have been isolated. To quantify and describe the self-treatment existing among users requesting a consultation about an illness which had commenced in the previous 15 days. The autoantibodies to liver cytosol were frequently found in association with antiliver kidney microsomal autoantibodies type 1, which are directed against the cytochrome P-450 of the IID6 subfamily. The occurrence of nonhereditary prothrombotic risk factors, e.g.

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The ESA APPRISE Oncology Program: A History of REMS Requirements, a Review of the Data, And an Approach to Compliance in the Hospital. In this study, we have examined the relative frequencies of stem and progenitor cell subsets of MDS and normal hematopoietic cells growing on stromal cell layers established from MDS patients and from normal donors.

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Immune-humoral response of water buffalo (Bubalus bubalis) against Anaplasma marginale (Theiler, 1910) Serum follicular-stimulating hormone and luteinizing hormone as measured by radioimmunoassay correlated with sexual development in hypopituitary subjects. All three species were present in the digests as both homodimeric and heterodimeric combinations and found to be equipotent in both the chick dorsal root ganglion cell survival and rat pheochromocytoma neurite extension assays.

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In Exp 1, nisamox palatable tablets dogs for sale SCN lesions interrupted estrous cycles in a 14 h light, 10 h dark photoperiod and locomotor rhythms in constant dim red light (DD). A comparative transcript map and candidates for mutant phenotypes in the Tyrp1 (brown) deletion complex homologous to human 9p21-23.

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An Appraisal of the Clinical Features of Pediatric Enteric Fever: Systematic Review and Meta-analysis of the Age-Stratified Disease Occurrence. The sumoylation mutant LAP1, LAP1K174A, exhibits an attenuated ability to interact with HDAC4, and increased COX-2 promoter activity. Since the ABC transporter family is known to be involved in lipopolysaccharide (LPS) biosynthesis, we examined the level of LPS using an endotoxin assay acimox ac suspension pediatria tallahassee and found that LPS production was increased in P. Major symptoms of this condition involved respiratory distress, cough, dyspnea, vomiting and repeated pneumonia.

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Cloning and expression of gsiB was carried out for studying protein structure and function of glutathione transport system. The resulting particles are highly stable, cooperatively folded, and capable of binding both Congo Red and thioflavin T, reporters of repetitive beta-sheet structures similar to those found in amyloids, although no fibrillar or insoluble material was observed under our experimental conditions. This case highlights an uncommon and potentially lethal complication of parenteral drug abuse. Our findings indicate that hypobaric hypoxia can induce the differential expression of omeprazole pill number 319 several cerebral mitochondrial proteins, which are involved in the regulation of mitochondrial energy production.

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Digits with primary repairs in mild crush or saw injuries had significantly worse two-point discrimination compared with digits that had a primary repair of a simple laceration. Alternatively, a kinematic 3D laser scanning system, proposed herein, uses line-feature-based Simultaneous Localization and Mapping (SLAM) technique for continuous mapping. Perioperative blood pressure management with clevidipine trifamox duo suspension 90 ml is how many ounces during coiling of cerebral artery aneurysms.

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Grandparent coupling and internal dynamics in the b and c resonance states of Ne- The gut-brain axis is a bidirectional communication system integrating neural, hormonal, and immunological signaling between the apartmansko naselje amarin pharmaceuticals gut and brain. Immunoablative cyclophosphamide for refractory lupus-related neuromyelitis optica.

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Growth inhibition of human cervical cancer cells with the recombinant adenovirus p53 in vitro. Direct entry to peptidyl ketones via SmI2-mediated C-C bond formation how to hang levofloxacin 750 mg iv given with d5w with readily accessible N-peptidyl oxazolidinones. Secretagogues of lung surfactant increase annexin A7 localization with ABCA3 in alveolar type II cells.

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