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KLF15(-/-) mice develop exaggerated neointimal growth, with evidence of increased SMC proliferation and migration within the neointima. The greatest binding response was observed in a direct reductive amination method with a long reaction period and increased the detection limit of direct binding of Salmonella antigen to 1x10(4) CFU/ml. When food was given ad libitum before trials, mutants needed more time and failed more frequently to find the chocolate. Expression of the alpha-fetoprotein gene in human breast cancer. A novel 18-L bioreactor for treating waste water was designed based on pneumatic agitation and semispherical baffles.

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Qualitative haemodynamic validation of a percutaneous temporary aortic valve: a proof of concept study. Distribution of a novel 57 kDa intermediate filament (IF) protein in the nervous system.

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All randomised trials (RCTs) that compared the use of a wound drain with no wound drain following plastic and reconstructive surgery of the breast (breast augmentation, breast reduction and breast reconstruction) in women were eligible. The purpose of our study was to evaluate the image quality and diagnostic performance of two-dimensional (D) turbo spin echo (TSE) and 3D T2-weighted TSE MR imaging in local staging of rectal cancer at 3T.

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Trigeminocerebellar projections to the posterior lobe in the cat, as studied by anterograde transport of wheat germ agglutinin-horseradish peroxidase. The authors sought to determine the inter-rater reliability of chest compression pattern classifications by human raters.

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From our data we conclude that BMP9 inhibits the migration and invasion of breast cancer cells, and promotes the osteoblastic differentiation and proliferation of bone marrow-derived mesenchymal stem cells by regulating cross-talk between these two types of cells through the RANK/RANKL signaling axis. its thinness and its innervation from the cervical segments of the spinal cord, the diaphragm is particularly suitable to characterize both central and peripheral events.

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Finally, we demonstrated cellular uptake of eLDL by valvular interstitial cells/myofibroblasts. Images of the normal spinal cord, normal variants (ventriculus terminalis, cyst of filum terminale) and spinal cord abnormalities (myelomeningocele, meningocele, diastematomyelia, tethered spinal cord and caudal regression syndrome) are presented. As binocular disparity must be scaled using an estimate of viewing distance, object depth can thus be affected through disparity scaling. Four weeks after the completion of therapy a repeat 13C-urea breath test was done to assess for cure. Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract.

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Recognizing distinct impacts of cognitive and mental health impairments and health care delivery needs on CSHCN outcomes may better direct future intervention efforts. External quality assessment for the detection of HCV RNA, HIV RNA and HBV DNA in plasma by nucleic acid amplification technology: a novel approach. Uterine artery embolization with methotrexate is an option for minimally invasive intervention in the treatment of CEP. Prevalence of sporadic inclusion body myositis and factors contributing to delayed diagnosis. Furthermore, the optimal Pluronic dispersant for MoS2 is found to be effective for a range of other 2D materials such as molybdenum diselenide, tungsten diselenide, tungsten disulfide, tin selenide, and boron nitride.

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We chose to use this combination of traditional biochemical techniques and proteomics to allow a more comprehensive analysis. Three patients with a birth weight under 1.500 g died in the first 24 hours. Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Alpha-Oxo Acids Assisted Transformation of FeS to Fe3S4 at Low Temperature: Implications for Abiotic, Biotic, and Prebiotic Mineralization. We obtained evidence that age-related changes in parietal and frontal components of the WM core network are dissociable in terms of their role in maintenance of perceptual representations and further manipulation of this information, respectively.

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Pathophysiological mechanisms of TNF during intoxication with natural or man-made toxins. Although strenuous effort has been made to improve its outcome, the mortality rate is only marginally decreased.

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Localization of 14 functional J regions in the human T-cell receptor alpha-chain locus. (Nuclear) magnetic resonance spectroscopy (NMR/MRS) methods can offer important insights into novel anticancer agents in order to accelerate the drug development process including time-course studies on the effect of a drug on its site of action (termed pharmacodynamics), in this case the cancer. Alkaline phosphatase and prognosis in patients with coronary artery disease. No perfect or near perfect indicators of clinical injury incidence exist. The influence of lipid on the conformation of human plasma high density apolipoproteins.

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Conscious and unconscious perceptions of self in children of alcoholics. Yet fewer than 20 percent of Americans have such plans in place. Movement of radioactive albumin in cerebrospinal fluid aids recognition of disturbances in flow. We here report a case complicated by metastatic infection, to our knowledge, the first one described in Northern Europe.

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Magnetic resonance imaging and computed tomography both have roles in the preoperative assessment of inner-ear abnormalities, cochlear nerve deficiency, and variant anatomy that may affect the decision to implant and the prognosis for auditory improvement and increase the risk for complications. The presence of a conserved family of G protein-coupled receptor kinases in vertebrates and invertebrates points to the central role of these kinases in signal transduction cascades.

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This is of particular interest owing to the close similarities between visna virus and human immunodeficiency virus (HIV), and the relationship between MHC class II and CD4, the cellular receptor for HIV. In addition to high grade, administered treatment and younger age at diagnosis, high Ki-67 expression seems to be independently associated with increased likelihood of recurrence in patients with DCIS. Cardiovascular disease, and the cardiovascular side effects of drugs, are essentially multifactorial problems involving interactions between many proteins, dependent on highly organized cell, tissue and organ structures. The bioconcentration kinetics of chlorpyrifos (O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate) in guppies (Poecilia reticulata) were investigated.

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We implemented a software tool called GENESIS for three different genome rearrangement problems: Sorting a unichromosomal genome by weighted reversals and transpositions (SwRT), sorting a multichromosomal genome by reversals, translocations, fusions and fissions (SRTl), and sorting a multichromosomal genome by weighted reversals, translocations, fusions, fissions and transpositions (SwRTTl). Diagnostic accuracy of the defining characteristics of the excessive fluid volume diagnosis in hemodialysis patients. The assays displayed consistent measurements of CA-125 independent of which other markers were simultaneously detected and showed good correlation with Luminex data.

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Analysis of genomic diversity within the Xr-region of the protein A gene in clinical isolates of Staphylococcus aureus. With the use of partial mouse PKD1 genomic DNA fragments amplified by PCR as probes, a genomic library of 129SvTer mouse in bacteriophage vector was screened by plagues in situ hybridization. Certain vasorelaxant natriuretic substances are also released during heart failure, perhaps in an attempt to offset excessive peripheral constriction and sodium retention.

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Maximum permissible levels of asbestos and other natural minerals with fibrous structure--necessity of verification Thirty-one patients were enrolled in the study, and twenty-nine patients with a mean age of sixty-seven years (range, fifty-one to eighty-five years) were available for one-year follow-up. Consequently, marked S phase arrest and apoptosis were observed in 7579 mAb-treated tumor cells.

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Pre-eclampsia (PE) is defined as pregnancy-induced hypertension and proteinuria, and is a major cause of maternal and perinatal morbidity and mortality. The evidence for statin use in secondary CHD prevention in postmenopausal women outweighs current evidence for use of estrogen replacement in this setting. No associations were found between brain measures and IQ measures in either group. We suggest junior doctors should employ the mnemonic LIED (latex, iodine, elastoplast and drugs) when taking a medical history. Influenza-associated pediatric deaths--United States, September 2010-August 2011.

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Finance leaders of hospitals with higher charges were more likely to express concern that price transparency would cause a reduction in hospital revenue by forcing them to lower charges. Gallstone patients with ABCB4 mutations may have low phospholipid-associated cholelithiasis syndrome, characterized by cholesterol gallstones and intrahepatic microlithiasis, along with recurrent biliary symptoms, despite cholecystectomy. We find that, like UV irradiation, pTpT increases the levels of p53, p21, and proliferating-cell nuclear antigen. Updated guidance is needed for intraoperative imaging systems and image-based planning systems.

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In conclusion, most gastric carcinomas express the well-known ECFs and the expression of GM-CSF is specific for signet ring carcinoma cells. The aim of the study was to define the added value of whole body FDG-PET in screening for distant metastases in patients with head and neck squamous cell carcinoma and risk factors. A high clinical suspicion combined with radiological imaging aids early diagnosis.

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We report the ultrasound, computerized tomography, positron emission tomography and magnetic resonance imaging findings of a 38-year-old man with a biopsy proven solitary neurofibroma of the spermatic cord. Acetate withdrawal from the growth medium during the exponential phase also led to rapid repression of most TCA cycle genes and a corresponding twofold increase in the expression of sucCD, which were strongly induced by citrate and succinate. The dilatation of the DV by means of stent implantation in the DV increased the blood flow volume rate in the umbilical vein. MDI 301 is a picolinic acid-substituted ester of 9-cis retinoic acid.

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Fibrositis is a common clinical syndrome characterized by diffuse musculoskeletal pain and multiple tender points on physical examination. Comparison of bleb morphology between trabeculectomy and deep sclerectomy using a clinical grading scale and anterior segment optical coherence tomography. L-serine, taurine, kynurenate, phosphoethanolamine and diverse amino acids in frontocortical dialysates of freely-moving rats: differential modulation by N-methyl-D-aspartate (NMDA) and other pharmacological agents.

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Etiology, pathophysiology, diagnosis, management guidelines in emergency cases The results support the hypothesis that the higher incidence of breast cancer among socially advantaged women is mediated partly by differences in exposure to reproductive factors, hormone replacement therapy and alcohol. In this paper, we present a simple, generic, mathematical model that elucidates a general method for targeting a chemical to particular tissues. Pharmacy files from the pool of adult patients receiving treatment at the ARV roll-out clinic between 1 April 2009 and 31 March 2012 were selected.

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This study aimed to compare receipt of screening mammography and the incidence of screen-detected breast cancer between metformin and sulfonylurea initiators. In contrast, incubation with prostaglandin F2 alpha led to significantly higher levels of secreted collagenase, while elastase failed to be detected in the supernatant of stimulated cells. This is not due to an isoform shift, since the N-CAM expressed by cultured cells (140 kD) is the same as that expressed by RPE in vivo. The average alcohol content of a drink was very similar for wine and beer, whereas in the case of spirits it was almost double. The results indicate the short-term stability of dietary patterns derived using either a priori or a posterior methods.

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For this, 6 pigs (30 kg each) underwent sigmoid resection and reanastomosis using the port as the sole laparoscopic access for conventional instrumentation. Uptake and metabolism of diclofenac in Typha latifolia--how plants cope with human pharmaceutical pollution.

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Thus, TG tests may be incorporated into decision-making protocols of prophylactic anticoagulant therapy in MM patients. Randomized trial of beta-lactam regimens in febrile neutropenic cancer patients.

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Although the potential of metacognitive strategies to reduce medical error is acknowledged, the framework promotes looking beyond the individual to consider the contributions to patient safety of identity issues, role uncertainty and the hierarchical clinical environment. Our previous finding that a correlation exists between the abo phenotype and the presence of a blood transposon in region 32E, led us to perform an extensive genetic and molecular analysis of the most significant aspects of the abo phenotype in different genetic backgrounds. Growth plates of rats sacrificed at 1200 were taller than those of rats sacrificed at 1800, but there was no difference between heights of growth plates from rats sacrificed at other times. Multiple studies have focused on inflammatory, immunologic, and environmental causes. The patient admitted to vigorous eye scratching, which we believe was the mechanism responsible for the process.

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Acetone carboxylase catalyzes the conversion of acetone to acetoacetate. A well described standard or reference serum and a standardized and reproducible test procedures could be used in different laboratories. The data confirm that the Pbhsp90 gene encodes a morphologically regulated and stress-responsive protein whose function is essential to cell viability of this pathogen. Pharmacoeconomics of levocetirizine in allergic rhinitis and chronic idiopathic urticaria: considerations for the USA.

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Blood samples before operation and week 1, week 2, and week 3 after operation were collected from each patient for HIT antibody screening by enzyme-linked immunosorbent assay using IgG antibody specific to the PF4/heparin complex. Changes in the structure of postburn keloid scars before and after cryotherapy Parameters of circulating erythrocytes were studied by impurity spectrum. It is generally believed that prostacyclin (PGI2) generation is greatly stimulated when blood vessels are injured, even by minor trauma, such as venepuncture.

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We characterized the phenotypes caused by and the molecular lesions of 52 ced-3 alleles. Gender effects on attention-deficit/hyperactivity disorder in adults, revisited. The disadvantages are: paralysis and atrophy of one side of the tongue, absence of expression of emotional and involuntary states on one half of the face, synkinesia, disorders of mastication. Metastatic tumors were identified at autopsy when the pregnancy was terminated 3 wk later.

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Effect of electrolytes on the microstructure and yielding of aqueous dispersions of colloidal clay. MMP12 was induced in arterial smooth muscle cells (SMCs) after acute vascular injury. The stoichiometries of binding were approximately 1 motor:1 tubulin heterodimer for all three motors. This study investigated the aerobic degradation of tetrachlorobisphenol-A (TCBPA) in sediment samples collected at three sites along Erren River in southern Taiwan. Evidence of headaches in individuals who deny having headaches during diagnostic screening.

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Prevention of Hypoglycemia With Predictive Low Glucose Insulin Suspension in Children With Type 1 Diabetes: A Randomized Controlled Trial. Moreover, the vimentin expression in these cultures seems to be independent of the mRNA levels of transcription factors associated with the differentiated liver phenotype.

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Hence, the present study investigated the effect of melatonin on AIS osteoblasts. Method 2 used a cellulose acetate membrane overlay which incorporates 4-methylumbelliferyl substrates, hydrolysis of which released a fluorescent product (4-methylumbelliferone). The combination of OEC transplantation and rhGDNF intravitreal injection will be more effective in promoting the recovery of visual function after incomplete injury of the optic nerve in adult rats.

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Electric field dependence of transient electron transport properties in rare-gas moderators. A co-immunoprecipitation experiment confirms this finding and suggests that a sizable fraction of nuclear U1 snRNP is associated with Gro. A search of the Google Scholar, Embase, Medline, and PubMed databases was carried out for published articles covering the use of pulse oximetry in bronchiolitis. An empirical therapy based on the clinical characteristics of cough had not been reported. Polyneuropathy was assessed by history and foot examination including pressure, temperature, and vibration perception and was classified as possible, probable, and severe.

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Inherited differences, such as single nucleotide polymorphisms (SNP), can influence the efficacy and toxicity of drugs. Expression of the alpha 4 neuronal nicotinic acetylcholine receptor subunit in the developing mouse hippocampus. We retrospectively reviewed the esophageal cancer patients who presented at our hospital from 1997 to 2004. Lesion location and volume were measured on T1-weighted magnetic resonance scans.

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5 year analysis of bacteriology culture in a tropical burns ICU. In addition to health problems associated with leg and bone disorders, the pig has been suggested to be a good model for human bone disorders. The toral neurons were bipolar and were distributed throughout the TS.