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Losectil (Omeprazole)
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Omeprazole

Losectil is a benzimidazole with selective and irreversible proton pump inhibition activity. Losectil forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic activities and does not antagonize histamine H2 receptors. Check for active clinical trials using this agent.

Other names for this medication:
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Obesity is a very common disorder directly linked with various diseases such as type-2 diabetes, hypertension and atherosclerosis. Early Experiences with Mobile Electronic Health Records Application in a Tertiary Hospital in Korea. Specific advice about how to change lifestyle behaviour to modify CVD risk factors was not always given by the practitioner, particularly when discussing behavioural risk factors.

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The lack of concordance between mother and child sera suggests that vertical transmission may not be the major route of transmission of HTLV infection to children in south-western Nigeria. In desert aerosol the nonspherical particles systematically increase side scatter with a maximum around a scattering angle of 120 degrees , while around 160 degrees the difference between scattering functions of spheres and nonspheres is small. This method-termed co-regulatory expression quantitative trait locus (creQTL) mapping-allows for evaluation of a more focused set of phenotypes within a clear biological context than conventional eQTL mapping. Interventions to encourage condom use among IDUs, particularly those with regular sex partners and those involved in the sex trade, should be further developed.

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Hq(4) and SUq(2) quantum group symmetries in diatomic molecules. CYP3A4 is the main human metabolizing enzyme, and many clinically relevant drug/herb-drug interactions (DDIs/HDIs) involving CYP3A4 are due to mechanism-based inhibition. After the study, the publishers of the information materials were provided feedback, including a discussion of our findings. We concluded that SCE analysis did not reveal any evidence suggesting that the dosage of CY used in this study had induced a permanent genetic damage.

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Purification and biochemical characterization of digestive lipase in whiteleg shrimp. More recently, scientific interest has focused on the presence and possible function of growth factors and their receptors in the human prostate and their autocrine or paracrine stimulatory effects in BPH development. The transcriptome of two genotypes with contrasting vernalization requirement was studied during primary (vernalization and short day conditions) and secondary induction (higher temperature and long day conditions) using an RNA-Seq approach. Self-crack-filled graphene films by metallic nanoparticles for high-performance graphene heterojunction solar cells. An increasing number of experimental beating heart animal studies describe simple transapical mitral valve repairs based on the direct endoscopic visualization of the left ventricle.

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Epidural analgesia for postoperative pain control following spinal surgery: paucity of evidence and need for studies. Analytical methods involving extensive sample pretreatment before CE analysis are considered, as well as strategies for directly injecting untreated biofluids.

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Multifamily group psychoeducation and cognitive remediation for first-episode psychosis: a randomized controlled trial. Quantitative assessment of contact and non-contact lateral force calibration methods for atomic force microscopy. However, HIV-seropositive patients were found among non-IVDU heterosexuals in all but the Czech network. Therefore, the relation between the time evolution of three optical sources related to the approach of the ball and the observed patterns of swing onset were evaluated quantitatively.

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Determination of the metal concentrations were carried out on 41 patients with myocardial infarction and 41 healthy controls matched for age and sex. Primary structure of a zinc protease from Bacillus mesentericus strain 76.

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Risk factors included mean arterial blood pressure and fasting blood levels of triglycerides, LDL-cholesterol, HDL-cholesterol, and glucose. Level of use is variable and can fall far short of recommendations. While many drug delivery systems have been developed for oral drug administration, the physiological components of the gastro intestinal tract remain formidable barriers to drug uptake.

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This study aimed to determine these effects on kidney allograft. Injury mortality rates for AI/AN children have decreased during the past quarter century, but remain almost double the rate for all children in the United States. The clinical picture and genesis of neurotrophic disorders in diseases of the peripheral nervous and vascular systems

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In the recent 18 months we analysed 13 patients with so-called therapy-resistant intestinal candidosis. The products of the papillomavirus E2 open reading frame play a key role in the regulation of the viral cycle. Drug interference with the sympathetic nervous system causes undesirable effects on the biodistribution of 99mTc-HDP in the mouse. Cooperative binding of EF-1A to the E1A enhancer region mediates synergistic effects on E1A transcription during adenovirus infection.

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In addition, most peptidoglycan recognition proteins, representing the almost complete collection of pattern recognition receptors, are part of the epithelial cells equipment. Cortistatin Inhibits NLRP3 Inflammasome Activation of Cardiac Fibroblasts During Sepsis. Conversely, moderate to severe mitral regurgitation is a negative predictive factor of spontaneous contrast. The frequencies of the restriction fragment length polymorphisms linked to the TNF genes were determined in 73 AS patients and 81 controls. The onset of disuse-related potassium efflux to succinylcholine.

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At the same time, the input conductance of these cells increased 2-3-fold. Lower availability of striatal dopamine transporter in generalized anxiety disorder: a preliminary two-ligand SPECT study.

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An awareness of this anatomical variation of innervation of the extensor digitorum brevis muscle is important for the correct clinical and electromyographic evaluations of deep peroneal nerve lesions. Further investigations of controlled breeding should incorporate other management strategies, such as better feeding and reduced heat stress, which are known also to improve buffalo reproduction. A majority of patients had a syndrome indistinguishable from schizophrenia without coarse brain involvement and shared similar variables predicting outcome of psychosis, thus raising important issues concerning their nosological status. Taken together, these results uncover a RAS-dependent mechanism mediating EGFR and VDR cross-talk in colon cancer.

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This experiment studied the effect of Cordyceps sinensis extract (CSE) on mice aged by d-galactose and castrated rats to analyse its antiaging effect. E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35. (1)The patient is invited to mentally go back to the hours immediately preceding the suicide attempts and reconstruct the sequence of thoughts, feelings and doings of the day. Two recent glenoid components with posterior augments have been designed to correct excessive posterior wear and retroversion. We first illustrate the methods by showing data from the 1950s, during which the effects of air pollution were much more pronounced, and then describe current methods that were developed to identify associations when the signal-to-noise ratio is much lower.

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This is beneficial not only in terms of the speed and accuracy of a calculation, but also in terms of the amount of useful information that may be obtained from a given simulation. Results of this trial will guide policy-making with regard to pharmacogenetic screening prior to treatment with nortriptyline or venlafaxine among older patients with depression.

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Membrane-bound glyceraldehyde 3-phosphate dehydrogenase activity was measured in erythrocytes from 43 patients with sickle cell anaemia, 24 heterozygous and 27 controls. Disease expression and molecular genotype in congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Non-parabolic voltage dependence of the EFM signal of subsurface CNTs in polymer composites was observed and a new mechanism was proposed taking consideration of capacitive coupling as well as coulombic coupling. To assess changes in the paracellular permeability of CNT-treated Calu-3 monolayers, we have measured the trans-epithelial electrical resistance (TEER) and the permeability to mannitol. Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity.

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Recently there has been expansion in knowledge concerning the pathophysiology of shock, inflammation and disseminated intravascular coagulation, factors affecting the outcome of HTRs. As underlying mode of action, this work is in line with recent studies from our group demonstrating that Archazolid A induced S-phase cell cycle arrest by interfering with the iron metabolism in leukemic cells.

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The immunological mechanism of an effective immunotherapy with paternal lymphocytes for unexplained recurrent spontaneous abortion (RSA) is not yet clear. This steric hindrance is so high that even an increase in the chain length by two CH(2) groups in NMEA-14 does not allow the formation of condensed domains. Diagnosis, treatment monitoring and prognosis of ASD symptoms could be facilitated with biomarkers to complement behavioral assessments. The authors designed and constructed a local gradient coil that produces large gradients and short rise times and connects to their clinical system. Andrectomy on both small and orange-claw males caused disappearance of the genital papillae and atrophy of the sperm ducts and testes.

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Torsade de pointes complicating acute myocardial infarction: the importance of autonomic dysfunction as assessed by heart rate variability. Its oncogenic role may be more important in young patients with HCC. The study provides evidence for the efficacy of ward-based team training using simulation. In both patients, peripheral nerve conduction velocities were reduced, while amplitudes of evoked potentials were normal. Using Western blot analysis and immunohistochemistry, we found that treatment with H(2)O(2) significantly enhanced phosphorylation of Etk and its downstream signaling molecule Stat1 in primary cortical neurons.

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Increasing the ratio of Si/Al and incorporation of Co into the catalyst framework improved the methyl bromide yield of light olefins over that obtained using standard SAPO-34. In an attempt to engineer T-cell reactivity to this peptide, a sequence motif found in many peptides recognized by human or mouse T-cells was introduced by amino acid substitution.

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These results indicate that Isc1p plays an important role in the regulation of cellular redox homeostasis, through modulation of iron levels, and of apoptosis. Five months after ACL reconstruction, landing kinematics differed between ACL-reconstructed and contralateral ACL-intact knees during a dynamic high-loading activity. Neurohormonal activation in acute heart failure: results from VERITAS. The proliferative potential of two types of tumor cells that did or did not express glial fibrillary acidic protein (GFAP) in 19 cases of high-grade gliomas, including nine anaplastic astrocytomas (WHO criteria, grade 3) and 10 glioblastoma multiforme (grade 4), was investigated by a combined staining technique, one-step silver colloid method for nucleolar organizer region-associated argyrophilic protein (Ag-NOR) and immunocytochemistry for GFAP. An Algorithm to Predict Success of Indirect Decompression Using the Extreme Lateral Lumbar Interbody Fusion Procedure.

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Medical record audits provided data on process-of-care outcomes. Applications of computational methods for predicting protein functional linkages are increasing.

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A permanent dialogue, during the course of the disease, is mandatory, in order to adapt the management to the objectives determined by the patients and the medical team. Therefore, how to design a robust genetic oscillator with desired amplitude, frequency and phase under stochastic intrinsic and extrinsic molecular noises is an important topic for synthetic biology.In this study, based on periodic reference signals with arbitrary amplitudes, frequencies and phases, a robust synthetic gene oscillator is designed by tuning the kinetic parameters of repressilator via a genetic algorithm (GA) so that the protein concentrations can track the desired periodic reference signals under intrinsic and extrinsic molecular noises.

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Given that maternal alloreactive lymphocytes are not depleted during pregnancy, local and/or systemic mechanisms have to serve a central function in altering the maternal immune responses. In this review, we will describe the current status of utilizing omics technologies of elucidating the impact of inulin and inulin-containing prebiotics at the transcriptome, proteome, metabolome and gut microbiome levels. A female patient with a skeletal Class III severe anterior openbite was treated using miniplates as the anchorage.

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Two of the patients required early withdrawal of D-penicillamine and a third patient, who had a good clinical and biochemical response initially, developed heavy proteinuria at 14 months. The present study demonstrated that the final-year medical students (interns) markedly benefited from undergraduate RPE at the medical school in developing rational prescribing skills compared with their classmates from a medical school with traditional pharmacology education.

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Experiments were performed on human melanocytes to elucidate the pigmenting effect of Ang II and the underlying mechanisms. Model selection in Bayesian segmentation of multiple DNA alignments.

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Long-term psychological effects of carrier testing and prenatal diagnosis of haemophilia: comparison with a control group. We should seek the support of foreign scientists and of Portuguese scientists living abroad for the technical evaluation of projects but they should not be asked to provide global strategies of investment in Portuguese science. The hyposecretion of growth hormone (GH) in maternal separation (MS) of rat pups is remarkably similar to the specific suppression of GH secretion to evocative tests in infants diagnosed with Reactive Attachment Disorder of Infancy (RADI). A study during repeated prolonged coronary occlusions in angioplasty These finding suggest that new therapeutic strategies targeting B cell function(s) can be developed for SSc.

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This evaluation draws attention to the need to take a systems approach and focus on contextual factors when implementing complex interventions. Effecting science, affecting medicine: homosexuality, the Kinsey reports, and the contested boundaries of psychopathology in the United States, 1948-1965.

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Association study of 10 genes encoding neurotrophic factors and their receptors in adult and child attention-deficit/hyperactivity disorder. To assess the effect of building dampness in dwellings on the occurrence of current asthma, and biochemical signs of inflammation.

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In this series of postoperative septic patients, we found a dissociation between sublingual and intestinal microcirculation. Ectopic hbox12 Expression Evoked by Histone Deacetylase Inhibition Disrupts Axial Specification of the Sea Urchin Embryo.

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In the control experiment thrombin generation was triggered with tissue factor reagent. When a fast voluntary movement is performed from a background condition of sustained antagonist muscle activation, there is often a decrease in antagonist muscle activity before the onset of the first agonist muscle burst (AG1) that continues until the onset of the antagonist muscle burst (ANT). We present a case of penile metastases in a 74-year-old male patient with prostatic adenocarcinoma in association with multiple skeletal metastases. Cell-cycle progress in obligate predatory bacteria is dependent upon sequential sensing of prey recognition and prey quality cues. SSB proteins from the extrachromatin fraction and chromatin were purified.

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Effects of flanking band proximity, number, and modulation pattern on comodulation masking release. Together with its adaptor p47, on the other hand, it regulates several membrane fusion events, including reassembly of Golgi cisternae after mitosis. Although in microorganisms (fungi, bacteria) and plants polyketide biogenesis is known to be catalysed by polyketide synthases (PKS), no insect PKS involved in biosynthesis of pheromones or defensive compounds have yet been found. The new aggressive cholesterol treatment goals call for a more advanced therapeutic approach to maximize the cardiovascular benefits associated with lower LDL-C levels.

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Estradiol suppresses mesangial cell type I collagen synthesis via activation of the MAP kinase cascade. Regional differences in crypt size, proliferative index, and distribution of proliferative cells along the crypt axis have been reported.

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During acidosis the contribution of I(hERG) to action potential repolarization is reduced and hERG may be less effective in counteracting proarrhythmogenic depolarizing stimuli. A practically available strategy is employed to improve the cycle life of lithium-sulfur batteries. Treatment of THP-1 cells with LPS induced production of IL-12, TNF-alpha, IL-8, and IL-10. Additional results suggest that changes in receptor affinity are involved in the pathogenesis of various types of experimental hypertensions because the amount of antibody required to block angiotensin was enhanced in renal (twofold), DOC (fourfold), and genetic (fourfold) hypertension.

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Although there is no evidence of effectiveness of interventional trials concerning macroangiopathy in diabetes mellitus, the focus of primary prophylaxis is based on the treatment of risk factors and optimal adjustment of metabolic parameters. Therapeutic hypothermia (TH) has been used in unconscious patients after near-hanging. Cognitive decline in late-life schizophrenia: a longitudinal study of geriatric chronically hospitalized patients.

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After the analysis of ImageMaster(TM) 2D Platinum software combining artificial comparison. Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and -independent nitrovasodilator relaxation.

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The results indicate for the first time that, contrary to established knowledge, even in osteoporosis the formation of large amounts of new bone is possible. A longitudinal study was performed for 24 months involving 114 patients. The results of this study indicate that the uptake of PAH due to indoor air pollution strongly affected the level of 1-OH-PY and that the main source of PAH in indoor air was the household use of coal for heating and/or cooking.

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This paper is a report of a study to develop and test the psychometric properties of the Occupational Coping Self-Efficacy for Nurses Scale. In particular, body surface temperature regulation was worse in upper SCIs than in lower injuries. The effects of each steroid depend primarily on its specific receptors, the nature of which could therefore provide a basis for classification of steroid hormone action. The general linear model was used to determine brain regions exhibiting activity differences between sessions conducted on different days, as well as between scans performed within the same session.

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After preliminary scientific data, the dentist commonly evaluates the success of a recommended clinical technique. Endoscopic cricopharyngeal myotomy for Zenker diverticulum using the harmonic scalpel. Morphine withdrawal was precipitated by administration of naloxone methiodide (5 mg/kg, s.c.) or naloxone (5 mg/kg, s.c.) on day 8. The SAPG undertook a survey to scope the current understanding and learning needs among nurses and midwives in a range of care settings across Scotland. The anterior borders of the clavicle and the acromion are not always aligned in the intact acromioclavicular joint: a cadaveric study.

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The indication and best time for intramedullary nailing of long bones in the multiple trauma patient is still controversial. In patients with this disorder, glycolipid deposition in endothelial cells leads to renal failure and cardiac and cerebrovascular disease. Anopheles gambiae exploits the treehole ecosystem in western Kenya: a new urban malaria risk? In order to confine the process, we used two advanced intrinsically 3D confined optical methods, namely: total internal reflection fluorescence (TIRF) and two-photon excitation fluorescence (2PE) microscopy.

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The process enables highly reproducible, catalyst-free synthesis of arrays of graphene nanosheets with reactive open graphitic edges facing upwards. Prevention of AMI Induced Ventricular Remodeling: Inhibitory Effects of Heart-Protecting Musk Pill on IL-6 and TNF-Alpha. Sensitivity of EEG upper alpha activity to cognitive and affective creativity interventions.

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This is the first example of Al2O3 ALD inhibition from a vapor-deposited SAM. Primary health care policy in Brazil: notes on Federal regulation and funding Despite this increase, chronic rofecoxib treatment did not attenuate the severity of acute PTZ-induced seizures and failed to alter kindling development or maintenance. Postoperatively, 4 of 13 patients who tried to conceive were successful. seroplex 10 mg vidal This study indicates that the rat apo C-I and ECL genes are closely linked, about 4.5 and 12 kb downstream of the apo E gene, respectively.

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192Ir high dose rate (HDR) fractionated interstitial brachytherapy was performed on two patients with tongue cancer with the aid of real-time intraoral ultrasonographic (US) guidance and the template technique. Extensive CGRP-immunoreactive fibers and darkly stained punctate structures, thought to be terminals, were concentrated in the dorsal cap and basal region of the middle cuneate nucleus. The Cech Symposium: a celebration of 25 years of ribozymes, 10 years of TERT, and 60 years of Tom. These data provide insight into the role of amoclan forte 125 mg methylprednisolone surgical exposure as a risk factor for cognitive and functional decline in older adults. Twenty-four preterm infants on continuous positive airway pressure were compared to six spontaneously breathing preterm infants.

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This study assessed the relative contributions of individual- and setting-level characteristics to implementation of a widely disseminated skin cancer prevention program. Those who survived 12 months or less (seven patients) or 40 months or more (seven patients) from catheterization were classified into short or long survival groups respectively. In this chapter, we provide an overview of the recent developments in our understanding of the repertoire of RBPs across diverse model systems and discuss the approaches currently available for the construction of post-transcriptional networks governed by them. Envelope variants circulating as nupentin information processing initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.

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Special attention is focused on the recombination (self-healing) of broken bonds. Evaluation of filter paper blood lead methods: results of a pilot proficiency testing program. These results suggest that medical professionals, during times of increased workload, first focus their attention on more acutely ill children with a complicated course and thus delay treatment of children who have less complicated courses but require time-consuming management and treatment. Ecdysterone has been found in a great many plants and animals and has some valuable pharmaceutical properties. Although ranclav 625 tablets their involvement in the carotenoid biosynthetic pathway is well understood, little is known about the mechanism by which these hydratases transform carotenoids such as lycopene into the corresponding hydroxyl compounds.

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To evaluate the changes of esophagogastric junctional adenocarcinoma (EGJA) and gastroesophageal reflux disease (GERD) among surgical patients from 1988 to 2012 in a Chinese high-volume hospital. To determine the conditions that a new test must meet to be a cost-effective alternative to established imaging tests. Our study showed that CI is a frequent complication after successful rAAA repair and could reliably be early diagnosed if surveillance colonoscopy was offered selectively in patients with more than three PRFs. To penamox suspension 12hp determine the feasibility that conjugation of hyaluronic acid-tethered bone morphogenetic protein-2 can be used to stimulate periosteal progenitor cells direct fibrocartilagenous attachment and new bone formation in an extra-articular tendon-bone healing model. An improved RT-IPCR for detection of pyrene and related polycyclic aromatic hydrocarbons.