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Liofen (Baclofen)

Liofen is an oral and injectable medication that relaxes skeletal muscles, the muscles that move the skeleton (and also called striated muscle). Chemically, Liofen is related to gamma-aminobutyric acid (GABA), a naturally occurring neurotransmitter in the brain. Neurotransmitters are chemicals that nerves use to communicate with one another. GABA released by some nerves causes the activity of other nerves to decrease. It is believed that Liofen, acting like GABA, blocks the activity of nerves within the part of the brain that controls the contraction and relaxation of skeletal muscle. Liofen was approved by the FDA in November 1977.

Other names for this medication:
Baclofen, Lioresal, Baclofene, Baclofeno, Baclon, Baclopar, Barambo, Clofen, Kemstro, Liofen, Lyflex, Miorel, Pacifen,

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Moreover, shock wave exposure altered the expression of functionally relevant genes in the hippocampus at 1 h and 1 day post injury. In these primary cultures, the fetal cells initially form random aggregates, which progressively acquire a tissue-specific pattern resembling that of the brain. The protein C anticoagulant pathway provides a mechanism for regulating the coagulation process through the selective inactivation of factors Va and VIIIa.

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Disturbed hemorheological parameters in SLE and RA women are related to the presence of CV risk factors and inflammation. Photoresponsive elastic properties of azobenzene-containing poly(ethylene-glycol)-based hydrogels. Hyperprolactinemia resolved with surgery in two patients and one developed diabetes insipidus as a complication. The aim of the study was assessment of environmental effect on typeability of AmpFISTR SGM Plus loci: D3S1358, VWA, D16S539, D2S1338, D81179, D21S11, D18S51, D19S433, TH01, FGA and gender marker amelogenin.

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This study is the largest to date examining PTEN status in breast cancer and the data suggest that the rate and significance of PTEN status differ between HER2-positive and HER2-negative disease. Primer extension assays with purified BALB/cJ and A/J proteins in vitro demonstrate that both forms of Pol iota are active but that they may differ in substrate discrimination, which may affect the formation of Kras2 mutations in mouse lung tumors.

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Patients were subdivided according to GOLD guidelines: 31 mild, 39 moderate and 28 severe. We explore here the use of a molecular dynamics technique based on swarm intelligence to identify the native states of two peptides and a Trp-cage miniprotein. Nevertheless, promising activity for these compounds has been suggested when combined with other, distinctly targeted agents.

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This article starts with a brief review of the thalamocortical system architecture, which is composed of the projecting thalamic nuclei, the thalamic reticular nucleus, and the neocortex. Experiments validate that the proposed method registers EAM and CT surface both automatically and accurately.

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Recommendations on the echocardiographic assessment of aortic valve stenosis: a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. Although higher SPPs are observed in POAG patients during the morning, lower DPPs are found during the night. Delivery of formoterol via the Certihaler or Aerolizer combines rapid relief with enduring control and provides convenient bronchodilation in patients with persistent asthma.

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Cancer cell targeting using multiple aptamers conjugated on nanorods. Even with these gaps, however, the historical beginnings of retroviruses can be traced back to events coincident with the prokaryotic invasion of primitive eukaryotes.

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This relaxation is mediated by nitric oxide (NO) or an NO-containing compound. Tissue samples were taken at age 10 (before obesity), 15 (moderate obesity) and 30 (developed obesity) weeks. Overall, 132 implants were inserted, 67 implants in the ibuprofen group and 65 implants in the placebo group. The aim of this study was to describe multidimensional factors and maternal feeding practices that may correlate with infant overfeeding in Latina mothers. LPS and TNF-alpha were most effective followed by IL-1beta, while the IFN-gamma had no effect on E-selectin expression.

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However, NBS for LSD relies on measuring enzyme activities, so the most severely affected individuals (usually patients with neuronopathic subtypes) will be detected together with patients with less severe disease. DRG neurons were positive for both the GBR1a and 1b antibody, but the former stained the cells much more intensely. The 3D interpolation method is an extension of cortical imaging technique. After changing the position, left upper lobectomy with lymph node dissection was performed via left posterolateral thoracotomy. The present data strongly suggest that capillarization of SECs plays a lesser role than collagenization of the space of Disse in the reduced exchange between sinusoids and hepatocytes in thioacetamide-induced cirrhotic rat livers, which appear to be quite resistant to CI-WR.

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In many cases it is an incidental finding on chest roentgenogram, and high-level function is usually possible before the onset of symptoms or degenerative changes. Lusitropic effects of dobutamine in young and aged mice in vivo. Effect of bound state of water on hydronium ion mobility in hydrated Nafion using molecular dynamics simulations.

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The study population comprised healthy children recruited in the nutrition study within the DIPP study in 1998-2003. (3) For these reasons, DNA analysis is now needed for clinical diagnosis of muscle disease. In all 16 cases with multiple lesions at least one of the lesions was asymptomatic at the time of the diagnosis. Although the precise pathways involved in the synthetic HLA peptide effects are not as well worked out, it seems likely that peptide binding to heat shock protein is disrupting normal events in T-cell activation, giving rise to an apparently permanent state of anergy. This study was undertaken to establish a feasible biomarker for IFN effects with respect to disease activity and effectiveness of IFN-suppressive therapy in SLE patients.

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Physicians clearly have difficulties in appraising the compliance behavior of their patients. A few studies indicate that a medically-induced abortion may increase the risk of reproductive failures in a subsequent pregnancy.

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Anomalous origin of the left coronary artery arising from the pulmonary artery in an infant: report of a case. According to diagnostic criteria of PSD, stroke patients and depression patients from Department of Neurology, First Affiliated Hospital, Anhui University of Traditional Chinese Medicine were assigned into cerebral stroke group (150 cases), depression group (151 cases) and PSD group (123 cases).

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Role of nitric oxide signal transduction pathway in regulation of vascular tone. It was non-mutagenic to Salmonella typhimurium strains TA1535, TA100, TA1538, TA98 and TA97 in the presence and absence of S9 mixture. Immune tolerance hinders the potentially destructive responses of lymphocytes to host tissues. Results showed significantly increased vascular endothelial growth factor and CD31 expression in the ischemic penumbra at 24 and 72 hours post infarction, mainly in neurons and vascular endothelial cells.

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Coat-colour dilution and hypotrichosis in Hereford crossbred calves in New Zealand is the same genetic disorder as that previously described in Simmental crossbred calves, and is linked to mutations in the PMel17 gene. Immortalized MSCs from adipose tissue (hASC) have been generated as good source of cells with stable features. Since these regimens did not work, her performance status got worse by cholangitis due to progressive liver metastases and anemia.

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Several mechanisms have been proposed to explain these rapid and long term effects and these will be discussed in this review. Standard approximations based on high incident energies, such as the Born-Bethe theory, are not suitable to simulate electron and positron tracks below 10 keV. Intravenous immunoglobulin (IVIG) is not recommended for acute or chronic myocarditis in Western nations owing to the lack of rigorous evidence, but it is widely used in other countries, including Japan. Our intervention, which eliminated the ability to order daily recurring tests, was implemented on June 11, 2014.

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This descriptive study in an urban tertiary care hospital explored the knowledge and attitudes of registered nurses regarding pain management. Approaches to N-methylwelwitindolinone C isothiocyanate: facile synthesis of the tetracyclic core.

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In Model 1, the system is either in working state on some demand or put to shut down mode on no demand. Here we describe the identification of the pif operon promoter by S1-nuclease mapping, and show that it is autoregulated at the transcriptional level and that its activity is modulated by integration host factor. An additional patient had central nervous system involvement upon arrival at our hospital and showed almost complete recovery.

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The aEEG is a simple but accurate and reproducible clinical tool that could be useful in the assessment of infants with encephalopathy. The Mini-Mental State Examination was taken by 862 subjects from the general population, all born in 1931 and 55 to 57 years of age at the time of the study. Results show that body-selective areas, whether defined by selectivity to headless bodies or body parts, preferred whole bodies over their sum of parts and successfully decoded body configuration. Since thoracoscopy under local anesthesia revealed purulent effusion, synechiae and fibrous septa in the thoracic cavity, synechiotomy was performed and we started antibiotic treatment with the diagnosis of acute bacterial empyema. Depending on local and general toxicity of an injected xenobiotic, orchiectomy should be considered as a treatment option of GSM.

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Studying PTM regulated events has always been a difficult task due to their labile nature. However, reactivation of members of the human herpesvirus (HHV) family, and of HHV-6 in particular, has been reported in patients with DIHS. Possible role of altered polyamine metabolism in gentamicin toxicity in OK cells.

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The aim of this study was to correlate the presence of CTCs with the commonest clinical and morphological variables. Significantly better results of the registration and drilling accuracy show up in group group 2.

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Histologic and molecular changes in the ipsilateral and contralateral epididymides of the rat in response to unilateral testicular torsion followed by detorsion. Compared with several benchmark models, the proposed method performs robustly and effectively for simulated and real biological data.

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Moreover, primitive progenitors are conserved to a greater extent under these conditions, as when cultured in direct contact with the stroma. Endogenous nitric oxide inhibits chloride transport in the thick ascending limb. Sinusoidal endothelial liver cells from the guinea pig were isolated by centrifugal elutriation and investigated as confluent monolayers. We suggest that this special structure is a protective device produced for the survival of F. Increasing trends and significance of hypovitaminosis D: a population-based study in the Kingdom of Saudi Arabia.

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Fetal and embryonic hemoglobin genes were up-regulated when patients had been severely myelosuppressed. Pulmonary toxicity with oxaliplatin and capecitabine/5-Fluorouracil chemotherapy: a case report and review of the literature. The percentage of urea was determined in and around the application site. Mosaicism most likely accounts for extended survival of trisomy 22. Assessment of peripheral nerve injury is a common task in forensic practice.

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More research is needed to better elucidate the trajectory of how and why social cognitive impairment develops in 22q11DS, and to explore possible relationships to psychiatric comorbidities like psychosis. Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality.

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Number of necrotic and apoptotic cells were increased in ischemic and reperfusion group with reducing tri carboxylic acid cycles marker enzymes, respiratory marker enzymes and decreasing of Bcl-2 expression. Attempts at a quantitative evaluation of the dissolving capacity of bacteria for natural phosphates

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Use of DNA photoaffinity labeling to study nucleosome remodeling by SWI/SNF. Management of complications following aesthetic procedures can lead to significant additional cost. Placebo-treated uninephrectomized mice were characterized by a transient increase in kidney IGF-I concentration preceding CRG and an increase in glomerular volume. Separation of subcellular membranes revealed increased GAP associated with a low density population of vesicles concomitant with growth stimulation as well as to the nuclear membrane, but not the nucleoplasm.

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A history of ipsilateral central venous catheter placement, or physical signs such as visible distended shoulder venous collaterals, and upper extremity edema are suggestive. When ascites or pleural effusion developed in patient with hepatic cirrhosis, complication of pulmonary tuberculosis must be considered.

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So any model of actual behaviour should capture the limitations on productivity inherent in the situation. Depletion of the maternal store of the localised mRNA encoding the T-box transcription factor VegT in Xenopus embryos has recently been shown to dramatically block endoderm formation and change the normal position of the mesodermal and ectodermal germ layers.

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The production of viral antigen after infection of MA104, HepG2 (derived from human liver), and CaCo-2 (derived from human colon) cells with various cultivatable human and animal rotavirus strains was compared using immunofluorescence tests. Insertional knockout mutants, allied with characterisation of recombinant GRs shows for the first time that amino acid stimulated germination in C. 329 consecutive male patients who had an orthotopic bladder replacement using the Z-shaped ileal neobladder between May 1990 and January 2009.

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Thus, there may be times in development when selection on the maternal, paternal or embryo contributions to development are more and less likely. A general synthesis of dirhodium metallopeptides as MDM2 ligands. Chronic intrathecal morphine exposure up-regulated protein levels and phosphorylation of spinal TAK1. Autographa californica M nucleopolyhedrovirus early GP64 synthesis mitigates developmental resistance in orally infected noctuid hosts.

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The cry properties of infants with a cleft lip and palate (CLP) and infants with a cleft palate only (CP) were quantitatively compared. Protective role of mitochondrial K-ATP channel and mitochondrial membrane transport pore in rat kidney ischemic postconditioning. The presence of Notch1 and hairy and enhancer of split-1 was also explored in brain tissues of patients with intractable temporal lobe epilepsy.

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Following ethics approval, children with persistent vegetative state were enrolled in a prospective, double-blind, placebo-controlled randomised trial. The authors also report that these experiential effects are disrupted in male mice carrying a knockout of the imprinted gene Peg3.

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Five-Year Period Prevalence and Characteristics of Anemia in a Large US Inflammatory Bowel Disease Cohort. We demonstrate that the equilibrium shape of the composite interface between superhydrophobic surfaces and drops in the superhydrophobic Cassie state under electrowetting is determined by the balance of the Maxwell stress and the Laplace pressure. A cylindrical standing wave ultrasonic motor using bending vibration transducer. Ultrasonic bone aspiration turbinoplasty is a safe and effective addition to the techniques employed for inferior turbinate reduction.

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According to an emerging paradigm, many of these changes are secondary to uncoupling of endothelial nitric oxide synthase. In biconcave glenoids, convex reamers remove a similar amount of bone as flat reamers, but offer a larger surface area while maximizing the correction of the retroversion. Methylation test was performed in 31 genetically confirmed FSHD patients and hypomethylation status was detected in all cases. These older patients typically have an increased incidence of comorbidities including diabetes, hypertension, and peripheral vascular disease. The gas-phase alcoholysis of protonated homoleptic alkoxysilanes.

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The majority of downregulated DEGs were functionally enriched in fat cell differentiation and the adipocytokine signaling pathway. In real life clinical practice across a diverse region, indacaterol and other long-acting bronchodilators improved health status and were well regarded by patients and physicians. In the present study, we examined the effect of gender, age, and in vitro culture on the basic properties (proliferation, differentiation, and immunosuppressive potential) of BM-MSCs. The topography and localization of motoneurons innervating the six extraocular muscles in the chameleon (Chamaeleo chameleon) was studied following HRP injection in each of these individual muscles. In vitro, initiation of differentiation of the human megakaryoblastic cell line CHRF-288-11 with phorbol 12-myristate 13-acetate leads to a very strong upregulation of rDEP-1 transcripts.

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This prostanoid is an important mediator because it stimulates ileal motility. Functional validation further corroborated the differential expression of genes coding for enzymes involved in chlorophyll metabolism, which correlates with the metabolite content of this pathway. The addition of enalapril to conventional management of congestive heart failure in Australia should improve survival and may provide a net reduction in treatment costs compared with conventional management alone. Additional analyses that can be performed with Cytoscape are also discussed. The purpose of this study was to identify the anxiety profile of undergraduate nursing students when learning a complex psychomotor skill, and to determine the effect of preclinical skill evaluation on student anxiety and performance when applying the skill in a patient situation.

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Diffusion weighted MR imaging is increasingly being used for the imaging of head and neck pathology. This phenomenon should be avoided when 5-fluorouracil is used with reduced folate in cancer chemotherapy. In contrast, ECHO subscale scores were clearly associated with the motivation to use amplification and might thus help to detect non-adherents. A soluble fusion protein of CD40 and human immunoglobulin, CD40-Ig, lovire 200 tablets inhibited the induction of B-cell cycle entry, proliferation, and differentiation by activated Th1 and Th2.

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Clean-up of urine samples includes a liquid-liquid extraction step followed by a solid-phase extraction step to separate HMMF and AMCC from other urine components. kaletra renal dosing We have developed a laparoscopic ultrasonography system with a convex-array probe.

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Drosophila is a powerful model system to study human trinucleotide repeat diseases. These data suggest an attractive therapeutic potential of IGF-1. We have determined that a zeffix 100mg filmtabletten 500mg qualitatively distinct stage of transcription is not detectable prior to DNA replication in transiently transfected cells. DNA repair machinery is considered to be one of these vital cellular components. The temporal evolution of electronic coherence originating from various electronic states is visualized via the fragment ions appearing after irradiation of the probe pulse.

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Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography. There was agreement between the CROM assessments using the Fleximeter and the CROM device. Radiologically, embryonal sarcoma reveals a characteristic spectrum of both solid and cystic features. GFLV and ArMV have a bipartite RNA genome and zovirax side effects tablets with usb are transmitted specifically by the ectoparasitic nematodes Xiphinema index and Xiphinema diversicaudatum, respectively. The presence of RAD-51-marked early recombination intermediates and 12 well condensed univalents indicate that IFE-2 is not essential for formation of meiotic double-strand breaks or their repair through homologous recombination but is required for crossover formation.

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Dose-dense chemotherapy for breast cancer: what does the future hold? Volume and fructose content of the seminal fluid correlated with the decrease in T. The duration of extracellular signal-regulated protein kinase (ERK) activation lansoprazole vs omeprazole efficacy pronunciation is critical for cell signaling decisions and probably determines whether a stimulus elicits proliferation or differentiation. In order to include effects of sampling, 10 snapshots from a molecular dynamics simulation are studied for each biotin analogue. The aim of this study was to investigate whether the cerebral oxygenation and hemoglobin concentration measured with NIRS could predict outcomes after pediatric cardiac surgery.

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3D QSAR studies of hydroxylated polychlorinated biphenyls as potential xenoestrogens. LeARN: a platform omapren 20 mg omeprazol for detecting, clustering and annotating non-coding RNAs. This Review provides a comprehensive overview of the current state of mRNA-based drug technologies and their applications, and discusses the key challenges and opportunities in developing these into a new class of drugs.

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Survival following elective colon cancer surgery has been almost unchanged since 2001. We present serological data, DNA genotyping and gene sequencing, monocyte monolayer assay and neutrophil oxidative burst test from a patient with the McLeod phenotype without clinical evidence of CGD. The median lies at 0.8 mg/dl in maternal serum withdrawn sub partu and in umbilical vein blood, and at 1.45 mg/dl immediately after ligation of the cord. Although absolute heart rate has been the principal means of automatic diagnosis, several new detection algorithms and methods are being investigated. This study pantoprazole side effects tingling tongue aimed to investigate whether a case/control classification model built on pathway level data was more robust than a gene level model and may consequently perform better in test data.

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The aim of the study was to investigate the prognostic value of C-reactive protein (CRP) in PE. To investigate whether, for a specific duration of type 1 diabetes, there is a significant change in gelnique 3 gel pump system the prevalence of proliferative diabetic retinopathy, gross proteinuria and peripheral neuropathy in those more recently diagnosed with diabetes (a period effect), in the Wisconsin Epidemiologic Study of Diabetic Retinopathy. The process of proton transfer is here analyzed for one-dimensional water chains adsorbed on metallic steps. Most disease-associated variants identified by genome-wide association studies (GWAS) exist in noncoding regions.

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coli was investigated, using selective cultivation with nalidixic acid, in grand-parent birds on arrival to Sweden and their progeny. Thus far, the results on the zemyc capsule filling association between nonexclusive and exclusive breastfeeding with regards to asthma are mixed especially in young ages.

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Investigation of radiation protection of medical staff performing medical podomexef antibiotique infection diagnostic examinations by using PET/CT technique. Plasma glucose and plasma insulin were similar (P greater than .05) for the clotting and the nonclotting milk replacers. The purpose of this study is to develop and evaluate a fully automated technique for accurate segmentation of the whole breast in 3-D fat-suppressed DCE-MRI. Therefore both exercise and brace could be prescribed for patients with LDP. Incidental Finding of Solitary Plasmacytoma in Thallium-201 Myocardial Perfusion Scintigraphy.

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In general, household income was highly associated with private cancer insurance. Ethanol and tert-butanol also had similar effects on liver amino acid concentrations, including an increase in the glycine concentration and decrease in the concentrations of glutamate, alanine, leucine, and tyrosine. Recently published data have revealed that these two receptors not only function independently, but also can influence each other via cross-talk between the different signaling pathways initiated by TNFR1 and TNFR2 stimulation. Signal intensities agopton takeda pharma of regions of interest (ROI) in the liver, spleen, and heart were measured. THE HYPOTHESIS: Conventional remineralization strategy depends on epitaxial growth over existing apatite crystallites.