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Genoxal (Cyclophosphamide)

Genoxal is used alone or in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection); cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that first appear as skin rashes); multiple myeloma (a type of cancer of the bone marrow); and certain types of leukemia (cancer of the white blood cells), including chronic lymphocytic leukemia (CLL), chronic myelogenous leukemia (CML), acute myeloid leukemia (AML, ANLL), and acute lymphoblastic leukemia (ALL). It is also used to treat retinoblastoma (cancer in the eye), neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children), ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), and breast cancer. Genoxal is also used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications or in children who experienced intolerable side effects with other medications. Genoxal is in a class of medications called alkylating agents. When Genoxal is used to treat cancer, it works by slowing or stopping the growth of cancer cells in your body. When Genoxal is used to treat nephrotic syndrome, it works by suppressing your body's immune system.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Clinical phenotype variability in patients with hereditary spastic paraplegia type 5 associated with CYP7B1 mutations. Thermal stimulation consisted of immersing a hindpaw in water at 52 degrees C for 2 min.

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Lund concept for the management of traumatic brain injury: a physiological principle awaiting stronger evidence. This exploratory study, conducted among 104 male workers free from cardiovascular disease (CVD), tested the association between burnout and two of its common concomitants--tension and listlessness--and cardiovascular risk factors. A key advantage of RP over PGC liquid chromatography is that retention times can be correlated to molecular weights, which can greatly facilitate further HMO identification using retention time prediction. Dehydration is a common problem in elderly patients, often resulting in hospitalization. The PMA does not inhibit the accumulation of IFN-beta mRNA in monocytes stimulated by Sendai virus in the presence of cycloheximide, indicating that the inhibitory action of the phorbol ester requires de novo protein synthesis.

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Teachers completed the Strengths and Difficulties Questionnaire for an ethnic diverse sample of 2,185 children ages 6 to 10 years. It is shoved significant changes of individual muscles contraction time course of ischemic m. In this prospective randomized study, patients had standard coaxial (2.8 mm incisions), microcoaxial (2.2 mm incisions), or biaxial microincision (1.2 to 1.4 mm trapezoidal incisions) phacoemulsification. The association between urbanicity and MDE was evaluated by Odds Ratios, controlling for potential confounders.

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The neuron as a time-coherence detector during stimulation from multiple synaptic inputs Amphetamines detected in exhaled breath from drug addicts: A new possible method for drugs-of-abuse testing.

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Positive and negative exchanges in social relationships as predictors of depression: evidence from the English Longitudinal Study of Aging. Purification and characterization of the periplasmic lysine-, arginine-, ornithine-binding protein (LAO) from Salmonella typhimurium. Present study demonstrates relatively good reporting standards in animal studies published in IJP.

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The adaptation hypothesis has been put forth as an explanation for why only a small percentage of susceptible individuals develop overt IDILI and severe injury, while the majority with susceptible genotypes develop only mild abnormalities that resolve spontaneously upon continuation of the drug. On the numerically predicted spatial BOLD fMRI specificity for spin echo sequences. Karyotypic analysis of hybrid and segregant lines, exhibiting proper AFP, albumin and AFP-HPRT phenotypes, revealed that the presence of human chromosome 7 was most closely associated with the AFP-extinguished state. This study aimed to examine rates of redeemed prescriptions of antidepressants and anxiolytics, used as markers for cerebral dysfunction in out-of-hospital cardiac arrest (OHCA) survivors, and examine the association between bystander CPR and these psychoactive drugs. Tunable doping of graphene nanoribbon arrays by chemical functionalization.

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The effects of anti-allergic agents on the hypersensitivity reactions to paclitaxel, an anti-cancer agent, were examined in rats. Venous thromboembolism and combined hormonal contraception: what are the implications for prescribing? (1) To determine convergent validity of an activity diary (AD) and accelerometer (Actical brand/Phillips-Respironics) in measuring physical activity (PA) in children with juvenile idiopathic arthritis (JIA).

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Fibroblast transplantation could be an alternative treatment strategy for the parkinsonian patient. Calcium polyphosphate as an additive to zinc-silicate glass ionomer cements. The long-term radiation-induced reduction of saliva output significantly contributes to the posttreatment morbidity experienced by these patients. After three days of treatment, morphometric and histochemical examinations of the small intestine did not show significant differences between treated and control rats. The hyperactive adolescents showed lower power of response in the right mesial prefrontal cortex during both tasks and in the right inferior prefrontal cortex and left caudate during the stop task.

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Re-engineering clostridial neurotoxins for the treatment of chronic pain: current status and future prospects. Data regarding unplanned hospital readmissions after TAVR in a real-world all-comers population are scarce.

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Disorders associated with excessive swelling of the lower extremities are common. Conformationally variable positions are less conserved in evolution. New strategies leading to a safe and efficacious food allergy treatment are required. Methylation of MYLK3 gene promoter region: a biomarker to stratify surgical care in ovarian cancer in a multicentre study.

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In order to study the osteogenic action of hydroxylapatite (HA) on the dental pulp, a pulp capping experiment was designed using the rat upper molar. Epicutaneous detection of transepidermally eliminated collagen by multiphoton microscopy: a possible non-invasive diagnosis method for acquired reactive perforating dermatosis. Using multiple-run molecular dynamics simulations we studied the interactions of L-BABP with lipid membranes of anionic and zwitterionic phospholipids.

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A gonadotropin-inhibiting substance in the urine of normal young children. This suggests that the Clb/Cdc28 kinase may have a relatively direct role in spindle formation. To study the functional significance of these mutations, the activated Ki-ras genes in two human colon carcinoma cell lines, DLD-1 and HCT 116, were disrupted by homologous recombination. Constitutive mutations of the LHR have been reported in familial testotoxicosis. Compression on the lumbar spine is 1000 N for standing and walking and is higher during lifting.

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This study suggests that gastrin is not essential for liver regeneration after partial hepatectomy. Laboratory studies on the efficacy of some molluscicides on Egyptian snails. There does not seem to be a perfect model for the inference of genetic networks yet.

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Abnormalities in serum lipids are important predictors of coronary artery disease. The central hip vertical axis: a reference axis for the Scoliosis Research Society three-dimensional classification of idiopathic scoliosis.

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Phylogenetic analysis and identification of different serovars of Mycobacterium intracellulare at the molecular level. Future studies should investigate the relationship between clinically relevant genotypes, phenotypes such as typologies, and treatment response. The force platform technique was used with automatic analysis that evaluated the position of the center point of force as a function of time. Coil performance was also evaluated using gradient and spin echo imaging at 8 T. Increasing the voltage, this lattice presents a spatial instability generating an undulating wall lattice, and to higher voltages it becomes zig-zag type.

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Steatocystoma simplex is a rare entity characterized by the presence of a solitary cutaneous cyst derived from a sebaceous duct or gland. Injections of fluid or septal cell suspension grafts into the dentate gyrus of rats induce granule cell degeneration. MicroRNA-30 (miR-30) is a known autophagy suppressor in some biological processes, while it is unknown whether this regulatory axis may be similarly involved in the development of atherosclerosis. Potent Fcalpha-mediated actions of IgA have previously been shown for myeloid cells from man, but much less is known in relation to murine cells. The mass was removed surgically and shown pathologically to be a nodule of ectopic thyroid tissue.

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Cell density-dependent expression of heparin-binding growth-associated molecule (HB-GAM, p18) and its down-regulation by fibroblast growth factors. Microfracture and drilling elicit a cartilage repair whose quality depends on subchondral bone repair. trachomatis specific antibodies was very high.(ABSTRACT TRUNCATED AT 250 WORDS) The large number of SNPs in genome-wide studies calls for a fast algorithm to output the optimal prioritization threshold for each SNP.

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Differential expression of Brn3 transcription factors in intrinsically photosensitive retinal ganglion cells in mouse. Future tools may benefit from the use of standard tools of measurement.

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Results show that the public has become more acceptant of prostitution over time. Monocyte deactivation has been identified as a major factor of immunosuppression in sepsis and is associated with a loss of surface human leukocyte antigen-DR (HLA-DR) expression on circulating monocytes. Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors. Development of liposomal systems of finasteride for topical applications: design, characterization, and in vitro evaluation. Mitochondrial DNA (mtDNA) was extracted and analyzed from the skeletal remains of 44 individuals, representing four prehistoric populations, and compared to that from two other prehistoric and several contemporary Native American populations to investigate biological relationships and demographic history in northeastern North America.

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Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival, neurite outgrowth and synaptic plasticity by activating the receptor tropomyosin receptor kinase B (TrkB, also known as NTRK2). In this study, we evaluated the significance of CHEK2 1100delC in predisposition to breast cancer by assessing its frequency in a material of 493 Korean breast cancer patients who had been screened for BRCA1 and BRCA2 mutations (42 patients had deleterious mutation of BRCA1/2). To probe into an effective method for treatment of endometriosis (EMs) and the mechanism.

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This study aimed to investigate the microsurgical anatomy of perforating arteries in the hypothalamic area, which are associated with diabetes insipidus. Artificial organelles: digital microfluidic platform for proteoglycan and glycoprotein biosynthesis. Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.

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There are few methods to control heavy intra-operative bleeding during cesarean delivery of placenta previa. Issues related to concentrating burn beds in a smaller number of facilities and external factors affecting their past and future operations merit additional review. The purpose of this study was to characterize cytogenesis and apoptosis in the developing retina of the Brazilian opossum, Monodelphis domestica. Early RBC transfusion in AUGIB was associated with a two-fold increased risk of re-bleeding and an increase in mortality, although the latter was not statistically significant. Besides positive and negative symptom control, they may improve cognition.

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The neurones were found to be excited by group I and II muscle afferents and afferents of skin, joint and interosseus nerves. A large, single-center, real-world study of clinicopathological characteristics and treatment in advanced annuntio vobis gaudium magnum habemus papa m movie reviews ALK-positive non-small-cell lung cancer.

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This review will summarize and discuss the available data regarding the potential role of CCR5 and miniature doxin dogs for sale its ligands in hepatitis C. The development of secondary vesicoureteric reflux (VUR) increases the risk of renal scarring and CKD. It was recently demonstrated that endo-N-acetyl-beta-D-glucosaminidases (ENGase) acting on N-glycosylproteins are produced by myxobacteria.

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Individuals with more severe COPD had greater OE and RA EMG both before and during arm movement compared to those with less severe COPD and controls. Transfusion of red cells in hematopoietic stem cell transplantation (TRIST): study protocol for a randomized controlled trial. In a first stage, stable granules were obtained at 20 degrees C, whereas fluffy acyclovir 400 mg tablets apple structures were observed at 30 degrees C.

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Activation of protein kinase C pathway by phorbol ester results in a proteoglycan synthesis increase in peritubular cells from immature rat testis. Increased cefuroxime axetil side effects pregnancy symptoms vancomycin use was not associated with an increase in VRE colonization over a 2-year period. In nonsteady-state systems, the accumulation of N in pools with slow turnover rates reduces N available for plant uptake and can be challenging to represent when initializing ESM simulations. A novel rhodium-catalyzed oxidative decarbonylative homocoupling of aromatic aldehydes to generate biaryls and diarylketones selectively and efficiently, triggered by the choice of different phosphine ligands.

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The effect of sulfonylurea drugs on rabbit myocardial contractility, canine purkinje fiber automaticity, zoton fastab orodispersible tablets android and adenyl cyclase activity from rabbit and human hearts. Insomnia symptoms were significantly associated with gastrointestinal regurgitation and headaches after controlling for demographic variables, apnea hypopnea index, ADHD, learning disorder or other psychiatric/behavioral disorder, socioeconomic status, and minority status. The data indicate that retention mechanism of IMP and vascular permeability are not affected in the cerebellum with CCD.

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Significance of laundry detergent residues from a dermato-toxicological risperidone medication for dementia viewpoint Discovering protein-DNA binding sequence patterns using association rule mining. Metastases may show histologic features of adenocarcinomas alone, of carcinoid tumors alone, or may resemble a composite neoplasm. We conducted a study including 210 patients with HCC and 206 healthy controls in Yunnan Cancer Hospital between January 2012-January 2014.

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Management of distal traumatic median nerve painful neuromas and of recurrent carpal tunnel syndrome: hypothenar fat pad flap. In contrast, infusion into the ventral hippocampus had no effect. The use of microorganisms for remediation of contaminated soil and groundwater has been limited by our incomplete understanding of how environmental variables influence the activities tadalis sx ajanta pharma viagra of microorganisms.