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Genoxal (Cyclophosphamide)
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Cyclophosphamide

Genoxal is used alone or in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection); cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that first appear as skin rashes); multiple myeloma (a type of cancer of the bone marrow); and certain types of leukemia (cancer of the white blood cells), including chronic lymphocytic leukemia (CLL), chronic myelogenous leukemia (CML), acute myeloid leukemia (AML, ANLL), and acute lymphoblastic leukemia (ALL). It is also used to treat retinoblastoma (cancer in the eye), neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children), ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), and breast cancer. Genoxal is also used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications or in children who experienced intolerable side effects with other medications. Genoxal is in a class of medications called alkylating agents. When Genoxal is used to treat cancer, it works by slowing or stopping the growth of cancer cells in your body. When Genoxal is used to treat nephrotic syndrome, it works by suppressing your body's immune system.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Lund concept for the management of traumatic brain injury: a physiological principle awaiting stronger evidence. This exploratory study, conducted among 104 male workers free from cardiovascular disease (CVD), tested the association between burnout and two of its common concomitants--tension and listlessness--and cardiovascular risk factors. A key advantage of RP over PGC liquid chromatography is that retention times can be correlated to molecular weights, which can greatly facilitate further HMO identification using retention time prediction. Dehydration is a common problem in elderly patients, often resulting in hospitalization. The PMA does not inhibit the accumulation of IFN-beta mRNA in monocytes stimulated by Sendai virus in the presence of cycloheximide, indicating that the inhibitory action of the phorbol ester requires de novo protein synthesis.

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Teachers completed the Strengths and Difficulties Questionnaire for an ethnic diverse sample of 2,185 children ages 6 to 10 years. It is shoved significant changes of individual muscles contraction time course of ischemic m. In this prospective randomized study, patients had standard coaxial (2.8 mm incisions), microcoaxial (2.2 mm incisions), or biaxial microincision (1.2 to 1.4 mm trapezoidal incisions) phacoemulsification. The association between urbanicity and MDE was evaluated by Odds Ratios, controlling for potential confounders.

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The neuron as a time-coherence detector during stimulation from multiple synaptic inputs Amphetamines detected in exhaled breath from drug addicts: A new possible method for drugs-of-abuse testing.

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Positive and negative exchanges in social relationships as predictors of depression: evidence from the English Longitudinal Study of Aging. Purification and characterization of the periplasmic lysine-, arginine-, ornithine-binding protein (LAO) from Salmonella typhimurium. Present study demonstrates relatively good reporting standards in animal studies published in IJP.

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The adaptation hypothesis has been put forth as an explanation for why only a small percentage of susceptible individuals develop overt IDILI and severe injury, while the majority with susceptible genotypes develop only mild abnormalities that resolve spontaneously upon continuation of the drug. On the numerically predicted spatial BOLD fMRI specificity for spin echo sequences. Karyotypic analysis of hybrid and segregant lines, exhibiting proper AFP, albumin and AFP-HPRT phenotypes, revealed that the presence of human chromosome 7 was most closely associated with the AFP-extinguished state. This study aimed to examine rates of redeemed prescriptions of antidepressants and anxiolytics, used as markers for cerebral dysfunction in out-of-hospital cardiac arrest (OHCA) survivors, and examine the association between bystander CPR and these psychoactive drugs. Tunable doping of graphene nanoribbon arrays by chemical functionalization.

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The effects of anti-allergic agents on the hypersensitivity reactions to paclitaxel, an anti-cancer agent, were examined in rats. Venous thromboembolism and combined hormonal contraception: what are the implications for prescribing? (1) To determine convergent validity of an activity diary (AD) and accelerometer (Actical brand/Phillips-Respironics) in measuring physical activity (PA) in children with juvenile idiopathic arthritis (JIA).

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Fibroblast transplantation could be an alternative treatment strategy for the parkinsonian patient. Calcium polyphosphate as an additive to zinc-silicate glass ionomer cements. The long-term radiation-induced reduction of saliva output significantly contributes to the posttreatment morbidity experienced by these patients. After three days of treatment, morphometric and histochemical examinations of the small intestine did not show significant differences between treated and control rats. The hyperactive adolescents showed lower power of response in the right mesial prefrontal cortex during both tasks and in the right inferior prefrontal cortex and left caudate during the stop task.

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Re-engineering clostridial neurotoxins for the treatment of chronic pain: current status and future prospects. Data regarding unplanned hospital readmissions after TAVR in a real-world all-comers population are scarce.

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In order to study the osteogenic action of hydroxylapatite (HA) on the dental pulp, a pulp capping experiment was designed using the rat upper molar. Epicutaneous detection of transepidermally eliminated collagen by multiphoton microscopy: a possible non-invasive diagnosis method for acquired reactive perforating dermatosis. Using multiple-run molecular dynamics simulations we studied the interactions of L-BABP with lipid membranes of anionic and zwitterionic phospholipids.

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Cell density-dependent expression of heparin-binding growth-associated molecule (HB-GAM, p18) and its down-regulation by fibroblast growth factors. Microfracture and drilling elicit a cartilage repair whose quality depends on subchondral bone repair. trachomatis specific antibodies was very high.(ABSTRACT TRUNCATED AT 250 WORDS) The large number of SNPs in genome-wide studies calls for a fast algorithm to output the optimal prioritization threshold for each SNP.

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Differential expression of Brn3 transcription factors in intrinsically photosensitive retinal ganglion cells in mouse. Future tools may benefit from the use of standard tools of measurement.

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Results show that the public has become more acceptant of prostitution over time. Monocyte deactivation has been identified as a major factor of immunosuppression in sepsis and is associated with a loss of surface human leukocyte antigen-DR (HLA-DR) expression on circulating monocytes. Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors. Development of liposomal systems of finasteride for topical applications: design, characterization, and in vitro evaluation. Mitochondrial DNA (mtDNA) was extracted and analyzed from the skeletal remains of 44 individuals, representing four prehistoric populations, and compared to that from two other prehistoric and several contemporary Native American populations to investigate biological relationships and demographic history in northeastern North America.

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Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival, neurite outgrowth and synaptic plasticity by activating the receptor tropomyosin receptor kinase B (TrkB, also known as NTRK2). In this study, we evaluated the significance of CHEK2 1100delC in predisposition to breast cancer by assessing its frequency in a material of 493 Korean breast cancer patients who had been screened for BRCA1 and BRCA2 mutations (42 patients had deleterious mutation of BRCA1/2). To probe into an effective method for treatment of endometriosis (EMs) and the mechanism.

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This study aimed to investigate the microsurgical anatomy of perforating arteries in the hypothalamic area, which are associated with diabetes insipidus. Artificial organelles: digital microfluidic platform for proteoglycan and glycoprotein biosynthesis. Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.

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There are few methods to control heavy intra-operative bleeding during cesarean delivery of placenta previa. Issues related to concentrating burn beds in a smaller number of facilities and external factors affecting their past and future operations merit additional review. The purpose of this study was to characterize cytogenesis and apoptosis in the developing retina of the Brazilian opossum, Monodelphis domestica. Early RBC transfusion in AUGIB was associated with a two-fold increased risk of re-bleeding and an increase in mortality, although the latter was not statistically significant. Besides positive and negative symptom control, they may improve cognition.

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