Gabictal is a new chemical compound designed as a structural analog of GABA that is effective in the treatment of partial seizures. In contrast to GABA, Gabictal readily penetrates the blood–brain barrier. In man, Gabictal has been demonstrated to increase GABA concentrations. Most probably the mechanism of action is related to events modulated through its interaction with a receptor thought to be associated with the L-system amino acid carrier protein. However, the primary mechanism of action remains to be defined.
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