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However, in Neuro-2A cells expressing partially active or overactive LPL variants, VLDL added to the cultured medium was able to induce the phenotypic differentiation similar to that observed in Neuro-2A cells expressing wild-type LPL. Macrophages in the presence of HAp microcrystals showed less ACP and LDH activity and higher intracellular calcium content than those in the presence of calcined HAp and alumina. Samples were obtained from 40 patients (15 men with age range 50 to 79 years, and 25 women with age range 47 to 87 years).

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Basal synaptic strength was impaired in slices from the ipsilateral, relative to the contralateral, hemisphere at seven days post-CCI and susceptibility to LTD was enhanced in the ipsilateral hemisphere at both post-injury timepoints. On O2 back flow and its correction in polarographic respiratory measurements Three patients received allografts from matched related donors and 3 patients from matched unrelated donors. A cohort study of alcohol consumption and risk of breast cancer.

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The stage is now set for developing a hybrid graft for in vivo studies. A Comparison of Three Approaches to the Reduced-Scaling Coupled Cluster Treatment of Non-Resonant Molecular Response Properties. Chemotherapy was administered until disease progression or unacceptable toxicity.

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A vaginal flap draped around the catheter provides the urethra, which is stripped through the dermal tube of the forearm flap acting as a corpus spongiosum. Song, sex and sensitive phases in the behavioural devebpment of birds. Eyes with high myopia were at the greatest risk for developing hypertension following implantation of a glaucoma drainage valve. Secondary outcome variables were pruritus, vomiting, sedation, pain report, pupillary miosis, and patient satisfaction. Histologically, the subarticular layer of cartilage cells was continuous in the joints with preservation of the articular soft tissue cover but was frequently interrupted in the joints where this cover was removed.

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Madin-Darby canine kidney (MDCK) cells exhibit many of the characteristics of cells of the cortical collecting tubule. The cyclin-dependent kinase Cdk1 directly regulates vacuole inheritance. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. Clinical evidence suggests that intracoronary thrombus formation is associated with a high incidence of late restenosis after successful coronary intervention in patients with myocardial infarction (MI). Endogenous TRAIL might promote resolution, at least in part, through modulation of the balance between pro- and anti-inflammatory cytokines, and the expression pattern of pro- and anti-apoptotic molecules of thyroid epithelial cells (TECs) and inflammatory cells.

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Relative cardiac expression of growth hormone receptor and insulin-like growth factor-I mRNA in congenital heart disease. Advanced HIV Disease at Enrolment in HIV Care: Trends and Associated Factors over a Ten Year Period in Cambodia.

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Addition of clarithromycin at low dosage (250 mg b.d.) proved to be useful, achieving a high eradication rate without increasing side-effects. Role of Orvosi Hetilap in the development of Hungarian gastroenterology. The use of inhibitors of prostaglandin synthesis for the treatment of acute nephro-ureteral colic of lithiasic origin

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The ototoxic potential of drugs has historically been uncovered by anecdotal reports that have led to more formal investigation. None of the patients underwent further surgery for frontal sinus disease.

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Notably, alcohol and cellular steatosis also induced autophagy in a synergistic manner, and also this was mediated via CYP2E1. There are no differences in MTBS to human dentin using either the air syringe or the suction tip to control the amount of moisture. Interaction in vivo and in vitro between the yeast fimbrin, SAC6P, and a polymerization-defective yeast actin (V266G and L267G). Collectively, the present findings demonstrate that, by coculturing MSCs with HUVECs, there was not only the promotion of osteogenic differentiation (and its enhancement, depending on the relative cell ratios used), but also a significant increase on MSCs proliferation. We also analysed the longitudinal change in SF-36 scores in both groups.

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So far, it has not been clear whether and how a motor controller could decode the responses of these neurons to prevent a blowfly from colliding with obstacles. In conclusion, mitral valve replacement with an on-pump beating heart technique via a right thoracotomy offers a safe approach when excessive dissection is required to place a cross-clamp to the ascending aorta. The pathology is compared with that found in cases of partial duplication (trisomy) and deficiency (monosomy) of chromosome 13 described in the literature. In the present study we find, using interleukin 2 (IL-2)-activated lymphocytes (LAK cells), that phosphorylation of a well-characterized 80-kDa PKC substrate increases during conjugation to target cells.

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The current study also suggests that hASCs have accelerated biochemical responsiveness to BMP-2 stimulus in human serum-supplemented culture medium compared with fetal bovine serum. In total Kura has been reported to be useful for 66 medical conditions and 1 spiritual application. Successful management of hyponatremia in heart failure patients requires a multifaceted approach in order to preserve end-organ function.

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Insulinoma and squamous cell carcinoma with peripheral polyneuropathy in an aged Sprague-Dawley rat. These results suggest that the improvement of immune functions, observed in previous work, after thioproline-enriched diet ingestion is due to a direct action of this thiol compound on immune cells.

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The reactivity became corresponding for normoreactive myocardial infarction. Cloning of the AKT2 promoter in a luciferase reporter plasmid further showed that Akt2 over-expression in cell lines is associated with increased AKT2 promoter activity suggesting that Her-2 modulates a signaling pathway involving AKT2 gene regulation. To test the efficacy in vivo, we have utilized a pig-to-mouse xenotransplant model. To compare hemodynamic variables during, and recovery quality following, anesthesia for feline blood donation using intramuscular ketamine-midazolam-butorphanol (KMB) versus inhaled sevoflurane in oxygen (SEV).

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Heel erosion was diagnosed most frequently, followed by interdigital dermatitis and contusion of the sole. The quick response to increased immunosuppression in our patient suggests an immune-mediated pathomechanism for recurrence of proteinuria. Factors predicting radiation toxicity in the treatment of three-dimensional conformal radiotherapy for lung cancer

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The combined influence of genetic factors and sedentary activity on body mass changes from adolescence to young adulthood: the National Longitudinal Adolescent Health Study. Holobiochemistry: the effect of local environment upon the equilibria and rates of biochemical reactions. We planned to evaluate the efficacy of epirubicin combined with cisplatin and ifosfamide in patients with localized primary osteosarcoma. Five HN patients were chosen, and for each patient, CBCTs were performed on three separate fractions spaced every 2 weeks starting from the first fraction.

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Similar results also were found with d-amphetamine (2 mg/kg i.p.) sensitization using a 10-day treatment regimen with testing on day 11. These effects could be perfectly mimicked by a small interfering RNA against DNMT3A and 3B, and partially compromised by DNMT3A/3B expression plasmids co-transfection, suggesting that miR-29s exerted the above tumor suppressive effects at least partly by silencing DNMT3A/3B.

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Are clinical measures of foot posture and mobility associated with foot kinematics when walking? Neurobehavioral effects of human immunodeficiency virus infection among former plasma donors in rural China. We find that CDK2 from HeLa cells contains three major tryptic phosphopeptides. Progesterone and medroxyprogesterone acetate decreased HUVEC thromboxane release in a progesterone receptor-dependent manner, without changes in thromboxane synthase expression and enhanced prostacyclin synthase gene and protein expression.

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Semi-structured interviews were conducted with 75 agency chief executive officers and program directors of 34 New York State-licensed mental health clinics serving children and adolescents. Ultrafast relaxation and modulation in the oxazine dye nile blue. Central nervous system lymphoma and cytomegalovirus retinitis accounted for the majority of the rise in the nervous system. Oral propranolol is widely prescribed as first-line treatment for infantile haemangiomas (IHs).

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In this report, we present four patients with type 1 diabetes of long duration (more than 20 years) who had multiple joint contractures (Rosenbloom syndrome) and who presented with reduced vision and advanced proliferative diabetic retinopathy. The splint, which is made of an elastic plastic material, was applied to 3 patients with an acquired ear defect. Several amino acids in numit RPS13 have changed from the one present in nucp RPS13 to the one present in mt RPS13, showing that numit rps13 is becoming more like mt rps13. To evaluate the clinical presentations and dominant symptoms of patients with postmortem proven cortical-basal ganglionic degeneration (CBGD) from one neuropathology center.

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The inhibition of NF-kappaB by DHMEQ may be an attractive therapeutic approach for keloids. The patient underwent surgical excision with an uneventful recovery. Immunohistochemical method was used to determine the expression of DeltaNp63 in 60 cases of NPC, 37 cases of nearby mucosa of the carcinoma, and 30 cases of chronic inflammation of nasopharyngeal mucosa. After five sessions of mobilizing the restricted metatarsophalangeal joint, the patient was able to return to track without complaint.

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Novel therapies that specifically target activation and expansion of pathogenic immune cell subsets responsible for autoimmune attacks are needed to confer long-term remission. HCV infection is a leading cause of chronic liver disease and a major indication for liver transplantation. Ice seal presence showed a strong positive correlation with ice cover and a negative association with 10 kHz environmental sound. L-myc mRNA was expressed in several other fetal tissues, particularly in fetal skin.

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Eighty-seven strains were found to be inagglutinable by these five sera but nevertheless could absorb agglutinins from such sera. Cholecalciferol modulates plasma phosphate but not plasma vitamin D levels and intestinal phosphate absorption in rainbow trout (Oncorhynchus mykiss).

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In spite of intensive care, with controlled pressure breathing and the last available vaccinia hyperimmunoglobulin, the patient died of pulmonary embolism although viral spread had ceased some days before. Data from nineteen patients with cervical spine metastasis were matched to thirty-eight patients with thoracic spine metastasis and thirty-eight patients with lumbar spine metastasis from a cohort of 183 patients with MSCC treated with posterior decompression and spine stabilization.

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Association between serum vitamin D and metabolic syndrome in middle-aged and older adults and role of supplementation therapy with vitamin D. l-separated Hylleraas basis functions in the perturbation expansion of atomic states: Accurate partial-wave energies of second order in 1/Z for the 1s2 ground state. One hundred outpatients with diagnosed ED (40 diabetic and 60 non-diabetic) received vardenafil at the initial dose of 20 mg and sustained dose of 10 mg once a week for 8 weeks, and their erectile functions were evaluated by IIEF and EQS.

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Scaling description for the growth of condensation patterns on surfaces. Stargazin involvement with bipolar disorder and response to lithium treatment. Using data from the Behavioral Risk Factor Surveillance System from 2000 to 2005, we find consistent evidence that higher taxes reduced smoking participation by older adults, especially those who are less educated and live in low-income households.

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By using this method, we constructed a quantitative atlas of membrane transporter proteins at the blood-brain barrier, liver and kidney in mouse. Rehabilitation in a community psychiatric service facility--success and failure during a one year period We also found that character order encoding was similar for single-morpheme and multiple-morpheme words, suggesting that morphemic status does not affect character order encoding. Doppler ultrasonography of the umbilical cord in complicated pregnancies. This discordance makes it difficult to compare disease and management practice.

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Punctate echogenic foci in spleen and increased echogenicity in renal cortex in sickle cell anemia. These findings raise the possibility of novel therapeutic approaches to vascular remodeling based on inhibition of VEGF signaling.

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All putative rearrangements were confirmed by FISH, microsatellite markers and/or MLPA assays, which also determined whether the imbalance was de novo or inherited. A randomized phase III trial demonstrated that vandetanib treatment is effective in patients with metastatic medullary thyroid cancer (MTC), leading to regulatory approval, but its use may be associated with toxicities that require specific monitoring and management. This is mostly due to inefficient delivery of the DNA plasmid into cells and nuclei. Quantitative regional analysis further demonstrated that while the multipotent cells derived from the cerebral cortex uniformly expressed PSA-NCAM, multipotent cells derived from generative zones contained equal proportions of PSA-NCAM-positive and -negative multipotent progenitor cells. These molecules can be used to immunomodulate vaccine responsiveness and have multiple applications in infectious diseases, cancer, allergy and autoimmunity.

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Cyclical intravenous pamidronate administration reduces bone pain, and increases bone mass and density. Fluorescence microanalysis was carried out to measure serum retinol concentrations.

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Sentinel lymph node biopsy (SLNB) is the standard treatment for breast cancer patients with clinically negative axilla. To assess the association between body mass index (BMI) and the quality of life of endometrial cancer survivors.

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Transcripts of interviews and focus groups were analyzed thematically by the research team. His symptoms were indicative of a paranoid psychotic disorder resulting from the use of corticosteroids.

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Cyclosporine reduces hepatic antioxidant capacity: protective roles of antioxidants. A basic understanding of tomographic cardiac anatomy is the foundation for proper use and interpretation of these new imaging modalities. General and Stereoselective Method for the Synthesis of Sterically Congested and Structurally Diverse P-Stereogenic Secondary Phosphine Oxides. As they are transcribed, RNA polymerase II transcripts (hnRNAs or pre-mRNAs) associate with hnRNP proteins and snRNP particles, and the processing of pre-mRNA occurs within these ribonucleoprotein complexes. An enemy-free nesting space is created when jays, an important source of mortality for hummingbird nests, alter their foraging behavior in the presence of their hawk predators.

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Obg comprises a unique family of high-molecular mass GTPases conserved from bacteria to eukaryotes. We find that individual females show plasticity in the date of first nesting each year, and that this plasticity depends on the climate from the previous winter.

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Our results showed significant overlap in gene expression changes induced by PNU-282987 and nicotine, suggesting convergent pathways triggered by these compounds. High-throughput sequencing demonstrated that sulfadiazine could impact on the microbial richness and diversity of SBBR treating mariculture wastewater.

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A pseudoaneurysm of the peroneal artery or one of its branches is rare after trauma. Mutational analysis confirms that the integrity of both these half-sites as well as their 1bp spacing are critical for binding of the ecdysone receptor. Distance learning courses were developed and implemented at the University of Dundee in response to this need. 5-OH-NF showed low capacity to induce DNA adduct formation and low potential as initiator to induce preneoplastic lesions-foci/nodules in the liver of rats. The combined detection of CD19, CD27 and IgD (or IgM) by flow cytometry (FC) analysis delineates five well-defined blood B cell-subsets: naive, switched (S) memory, double negative (DN) memory and CD27 IgD IgM (non-switched memory) B lymphocytes, and plasma cells (PCs).

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Alendronate reduced paw swelling at higher doses (over 0.1 mg/ kg) compared with its effect on BMD decrease (over 0.001 mg/kg). Production and characterization of a monoclonal antibody (BBH5) directed to ganglioside lactone. The arch structure of trabeculae in normal femoral head and its biomechanical significance. In all experiments the lesioned animals had spatial probe deficits on day 5 testing. To determine if race impacts the survival of patients with epithelial ovarian cancer in a large academic medical center.

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Thus, the aim of the present paper is to review data on the effect of supraphysiological doses of anabolic steroids on thyroid function, showing the danger that indiscriminate use of these drugs can cause to health. Bloinformatic analysis showed that a large fraction of the tick database entries have no clear matches in other sequenced genomes. Owing to its peculiar characteristics, as it is not to be regarded as a vaginitis in the strict sense of the word, it has been identified as anaerobic bacterial vaginosis. Osteoarthritis, a degenerative disease that commonly affects older people, is manifested by pain and disability. The sixth and eighth steps of histidine biosynthesis are catalyzed by an imidazole glycerol-phosphate (IGP) dehydratase (EC 4.2.1.19) and by a histidinol-phosphate (HOL-P) phosphatase (EC 3.1.3.15), respectively.