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Detrol (Tolterodine)
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Tolterodine

Detrol is used treat overactive bladder (a condition in which the bladder muscles contract uncontrollably and cause frequent urination, urgent need to urinate, and inability to control urination). Detrol is in a class of medications called antimuscarinics. It works by relaxing the bladder muscles preventing bladder contraction.

Other names for this medication:
Tolterodine, Detrol, Roliten, Detrusitol, Flochek,

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Implementation of a fast digital optical matrix-vector multiplier using a holographic look-up table and residue arithmetic. Tracheotomy can facilitate completion of palliative treatment in those patients with ATC and stridor. Autophagy, a self-digestion process that degrades intracellular structures in response to stress, such as nutrient starvation, is also involved in both cell survival and cell death.

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The importance of microtubules in mitosis makes them a superb target for a group of highly successful, chemically diverse anticancer drugs. CMR has the capability of offering additional information prior to surgical correction. These findings imply that ORF7 plays a role in neuropathy, highlighting a potential strategy to develop a neurovirulence-attenuated vaccine against chickenpox and herpes zoster and providing a new target for intervention of neuropathy induced by VZV.

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The findings are in keeping with the view that functional interruption at the neuromuscular junctions results first in failure to transmit the contractile impulse, and at a later stage in denervation atrophy. We sought to explore the potential synergistic antitumor activity and underlying mechanisms of the pro-apoptotic agent PAC-1 plus cisplatinum (Cis) in non-small cell lung cancer (NSCLC) cell lines. The Bibbulung Gnarneep Project: practical implementation of guidelines on ethics in indigenous health research. Circulating thrombospondin 1 level as a surrogate marker in patients receiving cyclophosphamide-based metronomic chemotherapy. One to 2 h after the first application, all three sunscreens were detectable in plasma.

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Subsequently, the RVS has required much work to correct errors by Medicare and the insurers that administer it, to improve procedure codes, and to develop codes and relative values for new procedures. To ascertain reliability, internal consistency and test-retest analysis were conducted. This article provides an overview of the evaluation and management of lower gastrointestinal bleeding (LGIB) in children.

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coli infection: differences in glycosyltransferase activities in intestinal mucosa of inbred CBA and DBA/2 strains. Antibiotic resistance and their significance in urogenital infections: new aspects We performed a cross-sectional study of 166 consecutive patients, aged between 29 and 87 years, with documented endometrial cancer who were referred to our clinic for treatment from January 1986 to June 1998.

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Five patients were treated with 6 weeks of intravenous antibiotics. Oral bioavailability and pharmacokinetics of trovafloxacin in patients with AIDS.

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Effect of barium sulphate-adsorbable proteins from serum on thromboplastin activity. We report on such a case of somnolence syndrome, review the literature and discuss the diagnostic and therapeutic problems. The use of spheroids for drug screening is hindered by technological complexities for high throughput generation of consistent size spheroids individually addressable by drug compounds. The generalized estimating equation was used to adjust for intereye correlations. Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations.

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The production of oxygen-derived free radicals in the endothelium was measured with 2,7o-dichlorodihydrofluorescein diacetate (DCF) using confocal microscopy. HLA-A29 as a potential risk factor for nonarteritic anterior ischemic optic neuropathy. Event-related potentials and secondary task performance during simulated driving.

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S 15535, a benzodioxopiperazine acting as presynaptic agonist and postsynaptic 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine. The aim of this study was to evaluate the maxillary sinus in a cohort of patients by means of clinical criteria and computerised tomography performed before surgery and after zygomatic implant placement (immediate function protocol). Except for women carrying genetic susceptibility to breast cancer, bilateral mastectomy is not considered the standard of care. Production of platelet-derived growth factor by human lung cancer. Once reactivated, previously consolidated memories destabilize and have to be reconsolidated to persist, a process that might be altered non-invasively by interfering learning immediately after reactivation.

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We investigate whether specific contacts between amino acids sidechains is a key factor in thermostabilisation in proteins. These patients were at high risk of poor outcomes such as myocardial infarction or death.

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After the onset of heatstroke, animals display hypotension and altered cardiac protein profiles, which can be reversed by whole body cooling. Biotechnological techniques of cross-linking and microencapsulation of hemoglobin result in blood substitutes that can replace red blood cells. Although varied drugs and therapies have been developed for lung cancer treatment, in the past 5 years overall survival rates have not improved much. The patient was successfully treated with intramuscular sodium stibogluconate. Fifteen male/female subjects who met the inclusion/exclusion criteria were included into this single-blind (preliminary phase) and double-blind (randomized phase) crossover study.

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Flow-mediated dilatation (FMD) of the peripheral arteries may be impaired in chronic heart failure (CHF), and this could contribute to the increased peripheral resistance and exercise intolerance that occur with this disease. In this study, we used immunohistochemistry and electron microscopy to examine activity-dependent changes in the distribution of Lfc in the neuropil of monkey prefrontal cortex. Few differences were noted in the drinking patterns of these men, although important differences were found in the prevalence of drug use over a 6-month period. In this update we present the recent worldwide experience and critically evaluate the role of minimally invasive radical surgery for patients with bladder cancer. If our data will be confirmed, maternal BMI should be considered in evaluation of umbilical Doppler velocimetry.

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To assess the expression of systemic lupus erythematosus (SLE) in Jewish Israeli patients according to ethnic origin. Buddhists and Protestants had comparatively low scores for paranoid ideation and overall symptom severity, with Catholics and Muslims having high ones. In contrast, there is a lack of consensus on the treatment of acute bipolar depression and long treatment options for bipolar disorder require more study.

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During surgery, severity of endometriosis was assessed using revised American Fertility Society scoring. An 11-year-old, female, spayed caracal (Caracal caracal) presented with a 3-month history of intermittent anorexia, vomiting, and weight loss. The TASER is a less lethal weapon seeing increased use by police jurisdictions across the country. The classes presented are beta-adrenergic antagonists (beta-blockers), acetylcholinesterase inhibitors, angiotensin-converting enzyme inhibitors, dieuretics, alpha-adrenergic antagonists, calcium channel blockers, cardiac glycosides, hypolipidemics (HmG-CoA reductase inhibitors and fibric acid), vasodilators and sodium channel blockers. Syphilis in children--the outcome of lacking vigilance and insufficient diagnostics

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The two Whitesides methods using a capillary meniscus and a mercury manometer were compared against a current electronic transducer method using identical 18-gauge bevel-tipped needles and varying diameter capillary tubing. In the past few decades, considerable progresses have been made in identifying the route of Glut4, the Rabs involved in controlling it, and more recently the connection between insulin signalling and Glut4 trafficking through Rab activity control. The proposed cluster analysis was proved to be reliable and the delivered classifications stable. The major priority in treatment of combined soft tissue and bone injuries in the maxillofacial region is the primary reconstruction and fixation of the bony structures, with suturing of the soft tissue injuries only after this has been achieved.

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Expression of human and mouse alpha-subunit genes has been examined in cells of the gonadotrope, thyrotrope, and trophoblast lineages to identify DNA sequences that mediate selective transcription of the alpha gene in these cells. Participants in the study were randomly assigned to one of two groups: one group listened to music during the procedure, and the other did not. However, full osteointegration requires a long time and may not be complete 3 years after surgery. This paper summarizes the results of the workshop and the follow-up discussions between the organizers and the BfS. Expression pattern of a newly recognized protein, LECT2, in hepatocellular carcinoma and its premalignant lesion.

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Human immortalized chondrocyte cell line lbpva55 was stimulated with TNF-alpha and treated with GlcN and NAPA. In contrast, the IGF2 gene is biallelic in expression in chickens, which are oviparous, and make no postfertilization contribution of maternal resources to the offspring. Familial hypercholesterolemia in the Czech Republic: more than 17 years of systematic screening within the MedPed project. Disseminated superficial actinic porokeratosis co-existing with linear and verrucous porokeratosis in an elderly woman: Update on the genetics and clinical expression of porokeratosis.

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PAX5-PML acts as a dual dominant-negative form of both PAX5 and PML. Dysregulation of such efflux mechanisms leads to iron accumulation in the CNS. Animals carrying TS/A cells that had been given doxycycline for induction of hGBP-1 expression revealed a significantly reduced tumor growth compared with mock-treated mice. Patients with IBD who attended Nancy University Hospital between November 2012 and May 2013 were included in the study. using retroperitoneal laparoscopy facilitated by balloon dissection the authors developed a new approach to the infrarenal abdominal aorta, in six pigs, to allow control of aortic blood flow.

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All incidents of bracket failure and debonding noted in patient records during the 2012-14 observation period were compiled by the other co-author, whom was blinded to the study and did not perform any orthodontic treatment on the study patients. Associations of background factors and health behaviours on the indexes were analysed by general linear modelling. Image guided surgery can be a useful aid to improve visualisation of anatomy and subsurface structures during minimally invasive surgery.

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Choosing the best post-mortem biological tissue source for chromosomal studies is a challenge for cytogeneticists. Neuropeptide FF receptors antagonist, RF9, attenuates opioid-evoked hypothermia in mice.

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Pituitary changes involved in prolactin secretion induced by mifepristone and naloxone during late pregnancy. The effects of mode of language representation on cognition and the strategies for cross-linguistic study are discussed. Several of these compounds, particularly indole-3-carboxylic acid, 4-hydroxybenzoic acid and all four aldehydes, increased considerably in concentration upon infection of roots with Pythium sylvaticum, as did at least some of them upon infection of leaves with Pseudomonas syringae pv tomato. Mucinous cystadenomas of borderline malignancy showed an intermediate degree of amylase immunoreactivity.

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Sarcoidosis in Arabs: the clinical profile of 20 patients and review of the literature. A total of 2208 patients ranging in age from 52 to 75 years in a substudy of the Systems of Support to Increase Colon Cancer Screening and Follow-Up (SOS) trial were randomized at year 3 to continued automated interventions (Continued group), which included mailed information regarding colorectal cancer (CRC) screening choices, and were mailed stool kit tests or to a group in which interventions were stopped (Stopped group). Clustering of the target sugars in proper geometric arrangement greatly enhances the binding by these proteins. This model assumes that slowly equilibrating N-invertomers undergo deprotonation (lithiation) at different rates and that the stereochemical outcome is established during the deprotonation step. We propose a systematic categorisation of cooperativity into cooperative aggregation, intermolecular (allosteric) cooperativity, intramolecular (chelate) cooperativity and interannular cooperativity and discuss approaches to quantify them thermodynamically using cooperativity factors.

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Whereas some drugs may act on the hypothalamus or directly within PVN neurons (i.e. Differences in insulin resistance and pancreatic B-cell function in obese subjects with isolated impaired glucose tolerance and isolated impaired fasting glucose. Responses to a 5-min anoxia were studied in cats with different taste sensitivity for phenilthiocarbamide (PTC). The results could potentially fill the translational gaps of in vitro/in vivo or preclinical species to human extrapolation of hepatobiliary elimination mediated by MRP2/Mrp2. Noninvasive detection of angiogenic activities is thus of great importance in cancer diagnosis as well as evaluation of cancer therapeutic responses.

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Ursolic Acid--A Pentacyclic Triterpenoid with a Wide Spectrum of Pharmacological Activities. Profile of efficacy and safety in the treatment of remittent-recurrent multiple sclerosis with interferon beta-1b

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We investigated the clinical and prognostic importance of whole blood global and site-specific DNA methylation in GC. Rods-on-sphere silica particles for high performance liquid chromatography.

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We anticipate that the experimental results could be caused by cell-to-cell adhesion or volume exclusion. We demonstrate this with a spin glass model that we generalize to include an active component. Thoracoscopic versus open resection for congenital cystic adenomatoid malformations of the lung. Ultraviolet stimulated melanogenesis by human melanocytes is augmented by di-acyl glycerol but not TPA.

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The best first-line treatment of pediatric achalasia was determined to be HM in two articles, PD in one article, and equal efficacy in one article. Its versatility makes it particularly helpful for the less experienced arthroscopic surgeon. Previous studies of the interaction of the haem undecapeptide (MP-11) with lipidated human serum albumin in aqueous solution have been extended to a range of MeOH/H2O solution compositions. However, the poor adherence to therapy is substantially below levels reported in clinical trials. Pulmonary shunts in severe hepatosplenic schistosomiasis: Diagnosis by contrast echocardiography and their relationship with abdominal ultrasound findings.

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The individual volume of early acute lesions versus chronic lesions involving dentin, and the fluorescein bound by resin was well documented in serial sections. Greater response to symbolic than non-symbolic stimuli occurred only in the left inferior frontal and middle temporal gyri, but only for words, and in the case of the left inferior frontal gyri, also for musical notation.

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Effect of concurrent use of ondansetron hydrochloride and dexamethasone against nausea and vomiting in lung cancer patients receiving cisplatin Besides classical etiologies of hyperprolactinaemia (pregnancy, pharmacological treatments, pituitary or hypothalamic perturbations), another less known cause may explain a spectacular idiopathic elevation of plasma concentrations of prolactin hormone. Insights into the conformations of three structurally diverse proteins: cytochrome c, p53, and MDM2, provided by variable-temperature ion mobility mass spectrometry. 99mTc sestamibi and 201 Tl are tracers that allow equivalent detection of myocardial infarction. The IMPALA study intends to improve adherence to lifestyle advice by involving patients in decision making on cardiovascular prevention by nurse-led clinics.

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Rarely, infections cause perforation and further fistula to the bronchial tree, lungs or pleural space. Primary testicular mucinous cystadenoma: Case report and literature review. The N-terminal domain containing TM1-6 of TAP1 is sufficient for dimerization with TAP2. Accordingly, the selection of relaxation parameter and number of iterations are studied in detail. Although relaxin primarily generates cAMP as second messenger, studies of relaxin signalling show that this does not conform to a classic G-protein dependent activation of adenylate cyclase: it requires additional cytoplasmic components, it can involve further coupling to PI3-kinase and PKCzeta and it is absolutely dependent on a tyrosine kinase activity linked closely to the relaxin receptor.

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This effect partly persisted after four weeks of morphine abstinence. Therefore, no relationship of the polymorphisms studied with economic traits was observed, as both breeds have respectively low carcass and milk parameters. The aim of this study was to establish whether blood sampling seasonality may influence total vitamin D concentration in a general population of Italian unselected outpatients. It is typically self-limiting but can result in ventricular arrhythmias and cardiogenic shock.

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These methods represent an advance in the way safety data from clinical trials can be analysed and presented. Cross-sectional studies, longitudinal studies, and meta-analyses that had appropriate control groups (patients matched for age, sex, and menopausal status), made comparisons with established databases, or defined thyroid state by TSH level or thyroid hormone dose were reviewed. More comprehensive research is needed to assess the relation between vitamin D and melanoma. TOA and TSA were calculated for 3 periods reflecting morning hours (6-10 am), afternoon hours (1-5 pm), and night hours (0-4 am).

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Although hypoxia and ischemia are known to be involved in the pathogenesis of cardiovascular disease, specific therapeutic targets still remain elusive. It codes for a very basic, hydrophobic, 35,000-Mr polypeptide, possessing a putative membrane-spanning domain. The structure of the human temporomandibular joint disc: a scanning electron microscopy study. Radiological vascular intervention combined with immunosuppressive drugs can be useful in selected cases.

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Scanning electron microscopy (SEM) observation illustrated that the modified bioactive glass particles were homogeneously dispersed in the PDLLA matrix. We interviewed 63 respondents, ranging from physicians to front-desk staff, from 27 primary care practices ranging in size, type, geography, and population size.

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The sample target for the survey was 300, consisting of 150 statin users and 150 OC users. In vitro studies have shown that both serum and endothelial factors induce EVE via tyrosine kinase intracellular signalling. MHC class II transactivator negatively regulates RANKL-mediated osteoclast differentiation by downregulating NFATc1 and OSCAR. In the 35th week of gestation a cesarean section was carried out after puncture of fetal ascites. These findings highlight a potential new approach for the correcting of MHC mismatches in cellular transplantation.

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Alpha-synuclein decreases arachidonic acid incorporation into rat striatal synaptoneurosomes. Transneuronal retrograde viral labeling in the brain loxin tablet stem and hypothalamus is more intense from the left than from the right adrenal gland.

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Adult T cell leukemia-lymphoma levofloxacin 500 mg posologia pollen is a rare disease with a high mortality rate, and is challenging for the clinician. Infection with the abomasal nematode, Ostertagia ostertagi, is an important cause of impaired productivity in young cattle in temperate parts of the world. Overall, the associations between adverse pregnancy outcome and exposure to radiation were weak and must be interpreted with caution with respect to implying a biogenetic basis.

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The application of an electric field has been shown to positively influence the bonding of dentin bonding systems (DBS) by improving adhesive impregnation into dentin. Most existing methods formulate the task as a low-rank matrix approximation problem. In the future the ddPCR technology could be advantageous for titration schenck rotec india ltd pune map of other viral vectors commonly used in gene therapy. The objective of present study was to survey and determine the reporting standards of animal studies published during three years from 2012 to 2014 in the Indian Journal of Pharmacology (IJP). Differential expression of centrosomal proteins at different stages of human glioma.

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Major conclusions are that (1) hatchery-reared juveniles exhibit abnormal lateral line morphology (relative to wild-origin conspecifics), suggesting that the hatchery environment affects lateral line structure, perhaps due to differences in the hydrodynamic conditions of hatcheries versus natural rearing environments, and (2) hatchery-reared salmonids have a high proportion of abnormal otoliths, a condition associated with reduced auditory sensitivity and suggestive of inner ear dysfunction. Thirty-eight percent of immediate TEs or PI placements at the time of mastectomy failed to progress to definitive reconstruction in patients receiving neoadjuvant therapy, suggesting that reconstruction with TEs or PI reconstruction should be used cautiously in this patient population. ECGs were obtained from 196 patients with limited and 77 patients with diffuse SSc included from our screening programme on cardiac complications. With this result, acyclovir cold sore cream breastfeeding older we consider that postoperative good survival can be expected by the aggressive surgical approach for cases of multiple primary lung cancer, despite it is difficult to distinguish multiple primary lung cancers and metastatic cancers preoperatively. Sequential study in rats of nasal and hepatic lesions induced by N-nitrosodimethylamine and N-nitrosopyrrolidine.

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External quality assessment of clinical biochemical assays in a medium non-academic, non-research hospital laboratory. British Thoracic Society Sarcoidosis study: effects tambac tablet reviews of long term corticosteroid treatment. Self-organized partitioning of dynamically localized proteins in bacterial cell division.

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Bilateral patellar tendon rupture secondary to repeated local tadalis 20 mg info steroid injections. The present review discusses the concept of stress and describes the mechanisms through which stress could influence headache progression. Whereas baseline functional impairment was not associated with subsequent manic symptoms, baseline functional impairment was significantly predictive of depressive symptom levels at four-month follow-up.

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The heel drop was chosen as the excitation method because it showed lower variability and could discriminate between different attachment pms prochlorperazine uses conditions. In the CA1 pyramidal neurons, changes in the distribution pattern of IR in particular cellular compartments, such as the nucleus and dendritic regions, was observed only in trained animals. Five cases of foreign textile bodies left in the peritoneal cavity are reviewed the corpus delictus was an abdominal field packing in 4 cases (in 1 case 2 packings were involved), and in one case a compress. After splitting off of the pre-fraction, glycosylering and passage through the Golgi apparatus, prorenin, which is biologically inactive, may be excreted immediately or be stored in secretory granules where activation occurs by splitting off of the pro-fraction. Analgesics and anti-inflammatory medications in sports: use and abuse.

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We present two patients with duodenal inflammation secondary to toothpick ingestion. 305, 191-197.), searches of the chicken norbactin diarrhea treatment genomic, EST, and HTGS databases did not reveal any evidence of the presence of this gene in birds. Screening questionnaires have revealed a potential burden of undiagnosed disease.

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However, this technology has not yet been used to its full potential. The RH map integrates genetic markers previously mapped on several rat crosses, increases the resolution of existing maps, and may provide a suitable basis for physical map construction and gene identification in this chromosomal region. Zidovudine prophylaxis after accidental exposure to HIV: the cefuroxime antibiotics Italian experience. Generation and role of calcium signal in adrenal glomerulosa cells.