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Darunavir
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Darunavir

Darunavir is an N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, Darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors. It has a role as a HIV protease inhibitor and an antiviral drug. It is a furofuran, a carbamate ester and a sulfonamide.

Other names for this medication:
Darunavir, Prezista,

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Differences between colorectal cancer patients and healthy people in fecal microbiota and metabolites The bicarbonate content of mineral water can replace alkalization therapy with potassium citrate and contribute to urine inhibitory power by increasing urinary pH and citrate excretion. Rosacea is classified into 4 subtypes, which determine the therapeutic approach based on skin care, topical antiinflammatory agents, topical and oral antibiotics and retinoids, and, in some instances, light-based therapy and surgery. Leptospirosis is endemic in Sri Lanka and this complication has been reported earlier in other countries but not in Sri Lanka to the best of our knowledge.

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Acute and chronic toxicity tests for malathion, diazinon, copper (Cu), mercury (Hg), lead (Pb), zinc (Zn), nickel (Ni), and iron (Fe) were conducted. Severe oligospermia or azoospermia developed in all subjects at the end of the loading phase.

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Low molecular weight heparin was administrated for three months. Enabling ideal selective solar absorption with 2D metallic dielectric photonic crystals. In the midst of controversies surrounding the social role and scientific potential of Child-Study, a new clinical psychology began to emerge. Perineural invasion (PNI) is a widely recognized indicator of poor prognosis in oral cancer patients, strongly correlating with aggressive tumor behavior, disease recurrence, and increased morbidity and mortality.

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How the response to the epidemic of HIV infection has strengthened the public health system. Mastectomy with axillary clearance versus mastectomy without it. In this paper, we calculated the dielectric function, the loss function, the magnetoplasmon dispersion relation and the temperature-induced transitions for graphene in a uniform perpendicular magnetic field B. Internal pressure by the distal phalanx of the hallux and the second toe and external compression from the shoes has been proposed as a reason for the pathology.

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Although there are some similarities to other documented syndromes, this previously unreported combination of features appears to constitute a new syndrome. In an attempt to distinguish the effects of patient selection from those of transplantation itself, we conducted a longitudinal study of mortality in 228,552 patients who were receiving long-term dialysis for end-stage renal disease.

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High potential of adhesion to biotic and abiotic surfaces by opportunistic Staphylococcus aureus strains isolated from orthodontic appliances. Asymptomatic individuals with 6LVs presented with different spinopelvic alignment compared to those with 5LVs. Identifying and preventing the well-recognized illnesses that lead to HF, including hypertension and coronary heart disease, should be paramount among the approaches to prevent HF. 1,001 recipients of domiciliary care were assessed three times in a 3-year period.

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Immunologic component in the pathogenesis of a progressive course following closed cranio-cerebral trauma Apparently healthy postmenopausal vegetarians are not significantly better in terms of carotid beta stiffness index, BAC, and BAD, but have significantly decreased BAR than omnivores. The method and results are provided as an approach that may be used as a basis to evaluate the risk of FMD outbreaks occurring in other wildlife/livestock interface areas of southern Africa.

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Self-organized criticality (SOC) became an important concept to describe neural systems. Correlation of the Sulphite Reduction Test with other Tests in the Bacteriological Examination of Water.

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Further assays included immune responses to the vector, static visual fields, pupillometry, mobility performance, and optical coherence tomography. This will require a shift in emphasis on the part of all concerned, and there is already evidence that this is beginning to happen. A recent clinical study revealed that clobutinol can prolong the QT interval compared to placebo and may thus cause cardiac tachyarrhythmias.

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To carry out a comprehensive research of the literature, it is necessary to consult an expert database, such as the Music Therapy World Journal Index, that guarantees an unequivocal level of completeness. Managing suspected venous thromboembolism in a mixed primary and secondary care setting using standard clinical assessment and D-dimer in a noninvasive diagnostic strategy. The possibility of elements of the nervous system in invertebrates originating from the parenchyma Physical fitness was measured by the Test of Physical Fitness, comprising nine different tasks including running, jumping, throwing and climbing. A Cluster-Randomized Controlled Trial of the Catheter Reminder and Evaluation Program.

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We have generated a line of transgenic zebrafish, Tg(dat:EGFP), in which the green fluorescent protein (GFP) is expressed under the control of cis-regulatory elements of the dopamine transporter (dat) gene. Furthermore, this extract inhibited the activities of cyclo-oxygenases (COX-1 and COX-2) and 5-lipo-oxygenase (5-LOX), also it attenuated the induction of interleukin 6 (IL-6) in differentiated THP-1 cells stimulated by lipopolysaccharide (LPS). The association between attention deficit hyperactivity disorder in adolescence and smoking in adulthood. Also, renal functions were significantly associated with both Hcy levels and inflammatory markers. Current biological work has monitored several aspects of memory, including activation decay, sustained activation, long-term connection change, and differential structures for episodic (hippocampal formation) and procedural learning.

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In a self-administration model, 3-O-methylnaltrexone treatment significantly increased both heroin and morphine intake during the first hour, suggestive of an antagonist effect. A prototype symbolic model of canonical functional neuroanatomy of the motor system. A matched group of non-anemic 1170 patients was used as a control group.

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To date, there have been greater than 25 reported cases of MCDF, but only one other publication has described an associated systemic comorbidity. The PA-induced shift of cytochrome c was observed from mitochondria to the cytoplasm. Postintubation tracheal ruptures (PTR) are rare but cause severe complications. Substitution of the SNR6 TATA box altered the site of transcription initiation in vivo, while substitution of sequences further upstream had no effect on SNR6 transcription. In contrast to malignant gliomas, the pleomorphic xanthoastrocytoma does not appear to require aggressive postoperative radiation therapy or chemotherapy.

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Long time MPI in allergic rhinitis resulted in some changes of tissue remodeling in nasal mucosa. All 4 cementless Wagner acetabular components appear to be osseointegrated with stable interfaces. Dual protective role of HO-1 in transplanted liver grafts: a review of experimental and clinical studies. In addition to staining doublet microtubules, anti-tektin C weakly labeled the central-pair microtubules in sperm tails from Patiria miniata. While these sociopathic behaviors of sometimes famous and powerful individuals have long been discussed, primarily within the realm of social science and psychology, here we offer a neurocognitive perspective on the possible neural roots of immoral and corrupt behaviors.

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Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis. ABCC6 mutations are responsible for the development of pseudoxanthoma elasticum, a rare recessive disease characterized by calcification of elastic fibers. The WR-PHI were not reflective of the ethical values and principles of critical health promotion. Periodontitis was induced by placement of a silk ligature below the gingival margin in dog molars. Noninvasive quantification of tumor volume in preclinical liver metastasis models using contrast-enhanced x-ray computed tomography.

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Contribution of imaging to our understanding of sexual function and dysfunction. Schools of reservation communities in 8 Indian Health Service areas. The unique I-A beta sequence of NOD mice was observed in the sister strain, CTS mice, and in one mouse of the original strain, outbred ICR mice. Hx triggered stronger phase 3-like activity and RE than atropine.

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The results presented in this and previous reports indicate that the antibacterial activity of dodine on P. We argue that specific information is more important for rejecting Intra pairs than accepting Old pairs. A Review of Selected Presentations From the 49th American Society of Hematology Annual Meeting and Exposition, December 8-11, 2007, Atlanta, Georgia. Simplicity, touch sensitivity, and visual/auditory feedback appeared to play important roles in satisfaction. To prospectively evaluate the effectiveness of post-operative endoscopic third ventriculostomy (ETV) in the management of persistent active hydrocephalus in a series of children operated on for a posterior cranial fossa tumour.

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Leukocyte concentrations trended down after initiation of chemotherapy, but it is uncertain how much of the decline was attributable to immunosuppression. A total of 42,000 pressures were recorded during a single prosthetic stance. Benefits and Challenges of Early Introduction of Left Ventricular Assist Device Placement: A Patient-Centered Perspective. In the present study, we investigated the effects of HPV-16 on hypopharyngeal squamous cell carcinoma and FaDu cells.

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Highly diastereoselective addition of lithio vinyl sulfoxides to N-sulfinimines: an entry to enantiopure 3-sulfinyl-2,5-cis-dihydropyrroles. The calibration graph was linear between 10 and 800 mg/l methacrylic acid, with an analysis time under 2 min. Reduced WWOX expression is associated with more aggressive phenotype and poor patient outcome in several cancers.

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The prognostic and therapeutic utility of new histopathologic parameters, such as tumor-infiltrating lymphocytes, are also being elucidated, and new protocols have been devised for the pathologic evaluation of breast specimens that have undergone neoadjuvant treatment. Loss of Thy-1 (CD90) antigen expression on mesenchymal stromal cells from hematologic malignancies is induced by in vitro angiogenic stimuli and is associated with peculiar functional and phenotypic characteristics. Extracorporeal Membrane Oxygenator Rotational Cannula Catastrophe: A Role of Echocardiography in Rescue. Gold(I) halide complexes of bis(diphenylphosphine)diphenyl ether ligands: a balance of ligand strain and non-covalent interactions. The respective diagnostic accuracies of these variables, and of age and grade, in detecting deep myometrial invasion were assessed with the use of histological findings as the standard.

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A total of 32 fine needle aspiration (FNA) specimens of metastatic prostate carcinomas were retrieved from the pathology files at MD Anderson Cancer Center. Sudan III pretreatment decreased blood concentrations of PL after intraportal infusion of PL at high doses (12.5 and 20 mg/kg), but not at a low dose (5 mg/kg). Potential for treatment with thrombolysis in an Irish stroke unit. Many of these results are probably applicable to other teleosts.

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To develop prediction equations to assist the clinician to derive cephalometric norms from the non-invasive investigations of ultrasonography (US) and 3D imaging. Redox-Robust Pentamethylferrocene Polymers and Supramolecular Polymers, and Controlled Self-Assembly of Pentamethylferricenium Polymer-Embedded Ag, AgI, and Au Nanoparticles.

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These results exclude 5 orders of magnitude in the coupling of chameleons to photons covering a range of 4 orders of magnitude in chameleon effective mass and, for individual models, exclude between 4 and 12 orders of magnitude in chameleon couplings to matter. Intravenous zoledronate improves bone density in adults with cystic fibrosis (CF). Experimental study on monitoring gene expression by noninvasive method in rabbit VX2 liver tumor model It is shown that in tangential electrokinetic measurements with porous films the porous structure makes contribution not only to the cell electric conductance (as demonstrated previously) but also to the observed streaming current. The program cost and cost-effectiveness of screening men for Chlamydia to prevent pelvic inflammatory disease in women.

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Molecular descriptors of agents were obtained from structure fragment reference databases and by quantum-chemical calculations combined with molecular modeling. The 51 exons unique to the long isoform of USH2A were screened for mutations among a core set of 108 patients diagnosed with USH2 and 80 patients with non-syndromic RP who were all included in a previously reported screen of the short isoform of USH2A. Methyl-ether-qinghaosu (artemether) was the most effective, with a potency approximately 10-fold greater than that of qinghaosu.

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The aggregation and self-assembly of the complexes were driven by electrostatic interactions between the polymer and the complex, and by terpyridine ligand pi-pi stacking and platinum-platinum (metal-metal) interactions. Community-dwelling women in natural menopause were recruited for a randomized, double-blind, placebo-controlled study of donepezil. Generally, African-American women tend to have an adverse cardiovascular risk profile when compared with women of other racial groups.

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By Western blot (immunoblot) analysis, protein GV8 was found to lose discontinuous epitope IV, which maps within the first 193 NH2-terminal amino acids. The percutaneous procedure allowed less soft tissue insult around the fracture site, a short hospital stay, a fast return to the preoperative level of mobility and fracture union. We prospectively collected data on mental and physical health related quality of life as well as sexual and relationship function in couples presenting for the treatment of infertility.

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Plasma miR-183 predicts recurrence and prognosis in patients with colorectal cancer. Strict recipient selection, possibly based on 123I-MIBG scintigraphy, the use of pulsatile circulatory assistance systems, improved CMV, morphometry and donor-recipient age matching, should optimize the results of a technique, whose efficacy is confirmed in this series. Air Force policy strongly discouraging the use of ephedrine-type alkaloid-containing dietary supplements appears to be supported.

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Because alpha-MHC is present only in small amounts in normal ventricles, a shift in favor of beta-MHC is of minor importance. Brainstem segmental arrangement of sucking rhythm generators for trigeminal, facial and hypoglossal motoneurons Effective handover within the health care setting is vital to patient safety. The pooled results and developed methodology can be used as diagnostic criteria for evaluation of the spinopelvic parameters, planning of surgical interventions and evaluation of the treatment effect. H2O2 induces rapid biophysical and permeability changes in the plasma membrane of Saccharomyces cerevisiae.

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Amide proton-solvent-exchange rate constants and 3JHN alpha coupling constants are evaluated. In this case-control study, we investigated the most suitable cell counting area and the optimal cutoff point of the Ki-67 index. Promoter hypermethylation of tumour suppressor genes as potential biomarkers in colorectal cancer. Neurophysin expression is stimulated by dopamine D1 agonist in dispersed hypothalamic cultures.

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This study aims at studying the MEFV gene splicing pattern in heterozygous FMF patients and healthy individuals, in an attempt to understand the mechanism underlying the disease in these patients. I defend against a certain line of attack the view that the conscious contents of color experiences are exhausted by, or at least matched by, the concepts brought to bear in experience by the perceiver. However, the effects of all FSs on cell viability, cell differentiation, and apoptosis were not simply explainable by their butyrate content.

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This approach may have some advantage when used for CTA with 64-section scanners in the specific circumstance of immediate postoperative imaging after placement of cerebral aneurysmal clips. The difficulties in using megapixel CMOS cameras for scientific measurements are discussed, and promising avenues for instrument development reviewed. Both the original non-integer data and transformed integer data on copy number were used for analyses.

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Observation of these tumors is indicated unless the patient is symptomatic or the tumor is greater than 1 cm or has atypical endoscopic ultrasonographic or histologic features. Recent studies have shown efficient and local drug delivery with nanoparticles, although the nanoparticle targeting mechanism for atherosclerosis has not yet been fully elucidated. The aim of the study is to analyze the differences between clinical presentation of first and subsequent episodes of depressive disorders in primary care patients.

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A disseminated gonococcal infection (DGI) must be suspected on appearance of tenosynovitis, polyarthralgia and skin lesions. Mitochondrial function was assessed by monitoring mitochondrial depolarisation. Few studies have assessed long-term trends or sex differences in its incidence over time. Although potential cycling has been widely used to activate PtRu electrocatalysts for methanol oxidation, little is known about the molecular/atomic level chemistry involved and also what constitutes the optimal activation.

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High temporal resolution and streak-free four-dimensional cone-beam computed tomography. In addition we give numerical and theoretical support to the hypothesis that the main LV belongs, under a suitable transformation, to the universality class of the Kardar-Parisi-Zhang equation.

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Retinal ICG-accumulation after ILM-staining during macular hole surgery? These therapies include the use of tyrosine kinase inhibitors and monoclonal antibodies for the treatment of cancer. The aim of the study was to analyse general health data, diagnostic and therapeutic procedures, pharmacological treatment and hospitalization of patients with atrial fibrillation (AF) who did not undergo AF catheter ablation and were in the care of outpatient cardiologists.

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We therefore studied sex differences in the response of serum cholesterol and lipoproteins to diet. Standard EMG techniques are used routinely in the evaluation of laryngeal dysfunction, but the feasibility of laryngeal SFEMG has not been established.

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Vibrio mimicus showed intracellular behaviour because bacteria were found to be localized in the cytoplasm of amoeba trophozoites and remain viable for 14 days. In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors.

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Timing of depo clinovir im ausland kaufen bei fiber arrival and dennervation of postsynaptic neurons is required for restoration of visual perception by regenerating axons. Acetaminophen toxicity in hepatocytes is attributed to generation of the toxic metabolite N-acetyl-p-benzoquinoneimine, leading to depletion of intracellular glutathione, alteration of redox potential and ultimately, cellular necrosis. MICs and minimum lethal concentrations (MLCs) were determined visually by comparison of growth in drug-treated tubes with growth in drug-free control tubes. Ocular adnexal IgG4-related lymphoplasmacytic infiltrative disorder.

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This review will give an overview of recent reports of engineered riboswitches, highlight recent developments and point out trends and problems in the field. Experimental zolt vs among models of HD and reflection on therapeutic strategies. No metastases or recurrence were observed 12 mo following surgery. Computer tomography showed tumour in the right bronchus, without pulmonary changes characteristic for histiocytosis X.

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This rejection was due to a critique from child psychoanalysts close to Anna Freud and also cipralex escitalopram 5mg uses from the teaching of Lacan: the first took the real mother-child relation extensively into account, while the latter only saw the internal object as a signifier. Then, the effects of spinal administration of TRPV4 antisense oligodeoxynucleotide (ODN) and mismatch ODN on CCD-induced mechanical allodynia were evaluated. In addition, it is known that Ag binding through the BCR causes apoptotic cell death at this stage of development.

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The panel has also allowed us to map several other DNA markers, genes (AMG, OA1), and nexpro l capsule side effects repetitive elements of the DXF22S and DXF30S sequence families relative to the various breakpoints. Expression of a Src family kinase in chronic myelogenous leukemia cells induces resistance to imatinib in a kinase-dependent manner. Some examples of clinical applications demonstrate that a detailed knowledge of orbital imaging anatomy is a prerequisite for successful interpretation of clinical MR images. Gender differences in the source location of the auditory evoked field (AEF) component N1m have been reported previously in a small group of subjects. We thus identify PML as the first protein degraded by SUMO-dependent polyubiquitination.

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(2) The safety profile of tacrolimus seems dose of bactrim in dogs similar to that of ciclosporin, but it is difficult to draw firm conclusions because of inadequate follow-up and recent progress in tacrolimus assay and dose-adjustment methods. On immunosuppressive therapy, all patients evidenced an adequate level of renal function.

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First, we conducted cross-species analyses to determine whether species with different breeding systems differed significantly with respect to mean individual seed size. This is apparently the first report on simultaneous quantification of more than four anionic salivary constituents using CE. This article proposes a novel classification system for open fractures of the hand, taking into account the factors unique to the hand that affect its risk for developing infection after an open fracture. Herein we report a one-pot procedure to prepare a family of homochiral dihydroxy-4-nitroisoxazolines 3. The allogeneic cancer vaccine could induce immune responses and protection against protica prefect protein beverage mix lung cancer, which had no significant difference with that of autologous vaccine.

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An accumulating body of preclinical studies has demonstrated that oral administration of plasma- or serum-derived protein concentrates containing high levels of immunoglobulins can improve weight, normalize gut barrier function, and reduce the severity of enteropathy in animal models. Novel roles of c-Met in the survival of renal cancer cells through the regulation of HO-1 and PD-L1 expression. Individuals from West Africa, the Mascarenes, southeast India and Malaysia shared a cluster. Detection of vancomycin-intermediate Staphylococcus aureus with the omep 40 mg kapseln mit updated Trek-Sensititre System and the MicroScan System. It is strongly suggested that muscle contractile activity plays an important role in the continuous and even distribution of dystrophin at the sarcolemma during development.

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Rubeanic acid as stabilizer of aqueous solutions of ascorbic acid. The literature was variable but nevertheless useful for the identification of evaluation standards. We modeled local cortical thickness flemoxin antibiotics and birth as a linear association with each motor symptom. Our objective was to investigate whether anastrozole, a potent aromatase inhibitor, could delay bone age acceleration and increase predicted adult height in adolescent boys with GH deficiency. The present study shows that behavior indicating mechanical allodynia can be rekindled after sympathectomy by intradermal norepinephrine and alpha-2 but not alpha-1 adrenergic ligands and the rekindling can be blocked by alpha-2 but not alpha-1 adrenergic antagonists.

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It is proposed that the three regent biogel d gloves for kids described genes could encode the key enzyme complex responsible for carbon dioxide fixation during autotrophic growth of the thermoacidophilic archaea. Decreased density and sensitivity of alpha 2-adrenoceptors in the brain of spontaneously hypertensive rats.