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Evidence that cysteine-166 is the active-site nucleophile of Pseudomonas aeruginosa amidase: crystallization and preliminary X-ray diffraction analysis of the enzyme. Anecdotal case presentations show the usefulness of the Porta-Stat in the dental office, hospital radiology department, and operating room for case documentation, growth monitoring, treatment effect, and clinical research purposes. Effects of inorganic mercury on reproductive performance of mice. The significance of bone biochemical markers and its application for clinics

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The objective of this study was to investigate outcomes for patients with brainstem metastases treated with stereotactic radiosurgery (SRS). In this review, we discuss recent advances in pharmacoepigenetics with a focus on DNA methylation. PCR fingerprinting of C albicans and C glabrata indicated strain persistence over 6 months in 10 patients and in 4 patients after 3 years. The suicide of Sylvia Plath is examined from the perspective of 15 theories of suicidal behavior and is found to fit best with psychoanalytic and cognitive theories of suicide, in particular those of Aaron Beck, Henry Murray, and Edwin Shneidman.

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PT-262 suppresses the phosphorylation of ERK and CDC2 associated with proliferation inhibition via a p53-independent pathway in human lung cancer cells. However, advances in related fields, such as cell cycle checkpoint control, have permitted the development of a hypothesis that may explain the relative tumor selectivity of fluoropyrimidine-mediated radiosensitization. Given the complex nature of modern health care systems, the ability to use this type of technique can enable health professionals to participate more fully in the analysis and implementation of health care improvement. Enzymes produced by a Pseudomonas species which inactivate inhibitors of certain viral hemagglutinins. Findings demonstrate that depressive symptoms explain disparities in incorrectly perceiving no diabetes risk by sex, age, and self-rated health but not race/ethnicity.

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Ipsilateral projections to the ventrolateral nucleus of thalamus arised from vestibular nuclear complex since the pattern of normal representations to mentioned thalamic nucleus were changed. Reported average daily frequency and incontinence episodes were also recorded. P-selectin (CD62) binds to subpopulations of human memory T lymphocytes and natural killer cells. We start by considering energy transfer models involved in the study of upconversion emissions, as well as well-established synthesis strategies to control the size and shape of rare earth upconversion nanomaterials. Sexual and physical abuse history in subjects with temporomandibular disorders: relationship to clinical variables, pain sensitivity, and psychologic factors.

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This article presents, for the first time to our knowledge, an all-fiber amplifier similariton laser based on a fiber Bragg grating filter. Together, these findings corroborate the viewpoint that mental time travel may be grounded in the embodiment of spatiotemporal information in a bidirectional manner. Signal sequences have been previously shown to be necessary and sufficient for targeting proteins to cellular membranes.

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Gallbladder emptying is reduced in many patients with cholesterol gallstones. Mannose-binding lectin gene polymorphism and early neonatal outcome in preterm infants.

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Ketamine is an anaesthetic interacting with several neurotransmitters. Alberta is achieving comparable cure rates with the Nicaraguan national tuberculosis program. Cost containment strategies by private hospitals: their effectiveness, importance, and use. Indeed, recent advances have shown that despite its invariant cell lineage, cellular identities can be reprogrammed, leading to cell conversion in vivo. While mortality rates after prison release are high, little is known about clinical risk factors for death.

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The expression of aromatase cytochrome P450 (P450arom) in the adrenal glands, testes, and placentas of fetal and newborn pigs was investigated. The matrix degradation by crovidisin may be responsible for the preferential detachment of ROS 17/2.8 osteosarcoma cells. The culture with acetate and no oxidoreductase expression had the highest level of HBP production. In a crossover study design, 6 swine under general anesthesia were subjected to a normovolemic hypotensive challenge induced by sodium nitroprusside. Taken together, these studies provide a detailed overview of the rice Di19 gene family, and suggest that the OsDi19 family may play crucial roles in the plant response to abiotic stress.

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In two patients, who developed myasthenia after bone-marrow grafting and who were followed before start of disease, antiidiotypic antibodies appeared before anti-receptor antibodies and before symptoms of myasthenia were present. Patients with acute or acute-on-chronic SCFE can be safely managed with straight-leg traction for up to 6 days, followed by in situ screw fixation without manipulation. These encapsulated molecules can be released by increasing the salt concentration in the eluent. Various techniques of spine fusion, with and without instrumentation, have altered the natural history of LBP unresponsive to conservative treatment. Alterations in the knee joints were confirmed by histopathologic and immunohistochemical analysis.

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Ulcerated hemangiomas of the lip can lead to increased scarring, loss of lip contour, and disfigurement. Automated protein model building combined with iterative structure refinement.

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Intra-oral malignant secondary tumours may present to dentists with signs and symptoms similar to those of benign, cystic or infectious processes. A negative birth experience: prevalence and risk factors in a national sample.

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The two independent variables, secondary mechanical and primary brain developmental mechanisms, were evaluated retrospectively. Locoregional recurrence of triple-negative breast cancer: effect of type of surgery and adjuvant postoperative radiotherapy. The G test followed by a post hoc Holm-Sidak adjustment was used for the statistical analyses to determine significance in the differential expression of proteins between the two strains. Diffusion tensor imaging of lesions and normal-appearing white matter in multiple sclerosis. Oral delivery of Lactococcus lactis that secretes bioactive heme oxygenase-1 alleviates development of acute colitis in mice.

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By maintaining an appropriately high level of suspicion for potential copper deficiency and obtaining a serum copper level, bone marrow failure due to this condition can be correctly diagnosed and treated. Detection of the 9-kDa vitamin D-dependent calbindin gene in a fruit bat (Rousettus aegyptiacus) fibroblast cell line. We conclude that the AHR complex integrates ligand binding and cyclic nucleotide signaling to generate an adequate transcriptional response. Synthesis of a new fluorescent conjugated polymer microsphere for chemical sensing in aqueous media.

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Convincing evidence has been obtained for its global effectiveness, but there is a debate about the processing fate of non-attended target features. Varietal origin of olive pollen is a major factor determining the diversity of Ole e 1 variants. Epistatic selection between coding and regulatory variation in human evolution and disease. Strict aseptic precautions during regular AVF cannulation are required. Additionally, three observers manually segmented 29 patient lung tumors five times each.

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Treatment of breast tumours frequently involves irradiating the whole breast to reach malignant microfoci scattered throughout the breast. Women enrolled on the Register are sent an annual letter reminding them that they are at increased risk of developing type 2 diabetes and encouraging them to get their blood glucose checked. Fifteen months after spinal PA resection, the patient is doing well, has regained the ability to stand independently, and has no evidence of any new or enlarging lesions. Acetabular morphology in MS has not been described in the literature. Escherichia coli hemolysin is the prototype of a large family of pore-forming toxins produced by gram-negative organisms.

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It was shown that the preliminary administration of bromocriptine decreased the degree of the withdrawal syndrome that correlated with the restoration of dopamine content and the normalization of the condition of D2-dopaminergic receptors in different regions of the brain. It is proposed that this cell death may have a physiological role in defence against certain viral infections which result in accumulation of cytoplasmic DNA.

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T cell engraftment in lymphoid tissues of human peripheral blood lymphocyte reconstituted SCID mice with or without prior activation of cells. To compare the performance of predictive models based on health care claims, health risk assessment (HRA), or both in prospectively identifying high-cost individuals with chronic conditions. Enhancing Practice Efficiency and Patient Care by Sharing Electronic Health Records. Computer-generated natural scenes were used as search stimuli and participants were required to look for a toy car in the scene. The present study shows that the brighter fat results from the multiple 180 degrees refocusing pulses, which eliminate diffusion-mediated susceptibility dephasing and suppress J-coupling modulation of the echo train.

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Effects of nitrate on the treatment of lead contaminated groundwater by nanoscale zerovalent iron. The features of the peripheral neuropathy due to standard-dose paclitaxel, which can be both motor and sensory, are well described. Combination nifedipine-beta blocker therapy has been shown to be favorable in the treatment of all varieties of angina, hypertension, and hypertrophic cardiomyopathy. There is relatively limited data regarding the use of the newer oral antifungal agents, e.g.

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Use of hypocaloric diets and a desire to be thinner characterized those asymptomatic subjects who were later to develop a partial syndrome. Protein data bank entries obtain distinct, reproducible flexibility characteristics determined by normal mode analyses of their three dimensional coordinate files.

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Dysregulation of fatty acid metabolism plays a pivotal role in the pathogenesis of insulin resistance in skeletal muscle. Single molecule approaches for quantifying transcription and degradation rates in intact mammalian tissues. QEEG changes during cardiopulmonary bypass: relationship to postoperative neuropsychological function.

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The mechanism of action of eribulin, preclinical data indicating antitumor activity of eribulin and data from Phase I and II clinical trials evaluating the efficacy and tolerability of eribulin are presented. The few studies that have explored how flying phobia is acquired have produced contradictory results.

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The frequency and extent of subjectively experienced adverse drug reactions such as anorexia, nausea and fatigue were related to depression mood disorder level. Secondary objectives included evaluation of plasma pharmacokinetics, long-term safety after repeated administration, preliminary antitumor activity, and pharmacodynamic activity. The most common relationship that developed was where the GP delegated responsibility for treatment to the CP. In evaluating this model, dose-response studies were conducted with lipopolysaccharide when a) it was administered intraperitoneally in saline or in Pluronic F 127 liquid, and b) it was administered intravenously to mice that had been pretreated with saline or Pluronic F 127 liquid. Experience with the treatment of malignant tumours of maxillary sinuses

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Our results suggest that dynamics of a gene circuit is mainly determined by its topology, not by detailed circuit parameters. The czc cobalt-zinc-cadmium resistance determinant, located on plasmid pMOL30 in addition copper, lead and mercury resistance determinants, arose by duplication of a czcICAB core determinant on chromosome 2, plus addition of the czcN gene upstream and the genes czcD, czcRS, czcE downstream of czcICBA. A systematic, meticulous and comprehensive analysis of existing publications regarding chronic lymphocytic leukemia with central nervous system involvement was performed. IQ scores did not deteriorate as a consequence of operation and some patients showed considerable gains in IQ with the passage of time. Controls included maternal and child health conditions at or around the birth, recurrent illnesses of mothers and children, and accessibility to and use of health care services.

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The mutants in RLM3(Col) also exhibited an enhanced susceptibility to Botrytis cinerea, Alternaria brassicicola and Alternaria brassicae. We examined insertion depth using the cuff depth and continuous chest auscultation method (CC method), compared with insertion depth determined by the marker method, to assess the accuracy of these methods.

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These findings suggest that CB cannot be considered a sufficient source of MSC for clinical use, although easily accessible. The results suggest that 4-year-olds do not understand that pretending requires mental representation. Spindlin1-induced transcriptional inhibition was greater for the HBV virus deficient for the expression of HBx than for the HBV WT virus, suggesting that HBx counteracts Spindlin1 repression. Estrogen binding sites in peripheral blood monocytes and effects of danazol on their sites in vitro.

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Psychosocial factors and survival of young women with breast cancer: a population-based prospective cohort study. Since both organic mercury compounds, unlike HgCl(2), do not readily enter intact cells, it appears that the specific steroid binding occurs inside the cell rather than at the cell membrane. These results show that isolation of cells from the inner mass of blastocyst represents an easy, reproducible and cheap source of neural derivates suitable for both in vivo and in vitro differentiation studies. In microbial fuel cells (MFC), wastewater is used as a fuel while organic and nutrient pollution in the wastewater are being treated.

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The results indicate that REA patterns can be used to determine variation both between as well as within species of Streptomyces. What is an adequate observation period to ensure that cessation of neurologic function is permanent? One patient required a full-thickness skin graft 3 months following the original surgery for a cicatricial ectropion. We considered it important to report this case because corticosteroids have been widely prescribed since about 1950 to treat a broad spectrum of somatic illnesses and because there have been many reports of both mild and acute psychiatric side-effects.

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401 General Military Hospital of Athens/Department of Audiology - Neurootology, Athens, Greece. We examined discharge characteristics of thalamic cells and intrathalamic evoked synaptic transmission in brain slices from wild-type, CaV3.2KO and CaV3.DKO mice through patch-clamp recordings.

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Persons with developmental disabilities are frequently exposed to interpersonal violence and crime, directed at themselves and others, and are in need of specific interventions tailored to their unique needs. However, this model cannot explain HLA-C allelic effects in disease or the impact of HLA-bound peptides. Toxic epidermal necrolysis (TEN) is the most severe of the Stevens-Johnson syndrome-toxic epidermal necrolysis (SJS-TEN) spectrum.

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The flap design for coverage of gluteal defects has a great impact on recurrence and complications. Post-partum pubic symphysis diastasis refers to an abnormally wide gap between the two pubic bones following delivery.

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Sudden cardiac death occurs in a minority of patients in the absence of structural or functional abnormalities. Kinetics of orally administered di(2-ethylhexyl) phthalate and its metabolite, mono(2-ethylhexyl) phthalate, in male pigs. Fas, a member of the tumor necrosis receptor superfamily, is 36 kD surface protein containing a single transmembrane region and induces apoptosis by Fas-Fas ligand binding. Selective inhibition of PHD2 in HCC cells might be considered as a new way to manage erythrocytosis in HCC patients. A nationwide investigation verified the frequency of HTLV-1 carriers among first-time blood donors and the occurrence of newly diagnosed adult T-cell leukemia/lymphoma (ATL) cases from 2007 through 2008.

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Collection of stool samples from children with sporadic diarrhoea and laboratory based microbiological analysis. The identification of Bcl-2 as a specific target and active partner in mutant SOD1 mitochondrial toxicity suggests new therapeutic strategies to inhibit the formation of the toxic mutant SOD1/Bcl-2 complex and to prevent mitochondrial damage in ALS.

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No epidemiologic studies from a truly comprehensive perspective consider environmental factors (EF) and personal factors (PF) as determinants of disability. Steady-state levels of NaPi-IIa in BBM were significantly enhanced, mRNA levels preserved, and phosphaturia reduced in the absence of megalin. Serial hormonal measurement of E2, P4, LH, and FSH serum levels. Specific IgE to fish extracts does not predict allergy to specific species within an adult fish allergic population.

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These stiffer fibrils respond mainly to unidirectional tensional forces, whereas the flexible thinner fibrils with helical subfibrils can accommodate extreme curvatures without harm, thus responding to multidirectional loadings. When administered to tumor-bearing nude mice together with monoclonal antibodies to the EGF receptor at a suboptimal dose which had no effect alone, inhibition of tumor growth was markedly enhanced. Sequence quality surrounding the SNP under test is also crucially important. However, most chemists and physicists are unaware of how the observed and/or calculated spin orientations are related to the local electronic structures of the magnetic ions.

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Integrating multiple clinical information systems using the Java Message Service framework. The surgery involved total resection of the tumor and resurfacing of the gap in the superior canal. Gastrin-releasing peptide induces itch-related responses through mast cell degranulation in mice. Whole blood viscosity is a key determinant of the work of the heart, and elevated blood viscosity appears to be both a strong predictor of cardiovascular disease and an important pathophysiological factor in the development of atherothrombosis. Monochorial vascular communications also can be responsible for twin transfusion syndrome, disseminated intravascular coagulation at birth and disruptive structural defects.

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In surface models, the whole courses of III, IV, and VI and circumjacent structures could be explored freely three-dimensionally. A 67-year old woman who had been taking D-penicillamine for 15 months for rheumatoid arthritis was hospitalized due to the development of a bullous eruption and proximal muscle deficiency.

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The blood samples were collected and analyzed for biochemical assays and whole blood DNA was used for mRNA expression of AQP4 using RT-PCR. We aimed to assess the effect of ART use by patients infected with HIV-1 on risk of transmission to their uninfected partners. All eight D-aldohexoses and aldohexoses derived from the non-reducing end of disaccharides were investigated by variable-wavelength infrared multiple-photon dissociation (IRMPD) as anions in the negative-ion mode. The power increases rapidly at first as the control sample size increases, then levels off at a few tens of thousands of control units tested and thereafter remains almost constant up to the historical control.

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To determine the financial and psycho-social impact of participation in clinical trials of patients with BCR/ABL-negative myeloproliferative neoplasms (MPN). The transcription factor p63 is critically important for skin development and maintenance. Analysis of cKox1 demonstrated that Kox1 is a single-copy gene that is expressed in a variety of hematopoietic and nonhaematopoietic cell lines.