Abilify, defined as a third-generation antipsychotic drug (APD) due to its unique pharmacological profile, represents an innovative therapeutic tool for major psychiatric disorders. Its modulatory properties on different neurotransmitter systems (see section: Overview of the pharmacological profile) highlight a drug with a broad pharmacological profile and clinical effectiveness in the acute and long-term treatment of different psychopathological conditions, as demonstrated in clinical trials. Abilify was shown to be effective and well tolerated in short- (4–8 weeks) and intermediate- to long-term (26 and 52 weeks) clinical trials for the treatment of schizophrenia and schizoaffective disorder. The data on Abilify efficacy and tolerability in schizophrenia have been recently reviewed, and support the overall effectiveness of this antipsychotic for the short- and long-term treatment of schizophrenia. Second-generation antipsychotics have been shown to be equally, or more, effective than classic antimanic agents, such as lithium and valproate, in the treatment of mania associated with bipolar disorder. Abilify was also shown to be effective and well tolerated in the manic and maintenance phases of bipolar disorder, in monotherapy as well as in combination with mood stabilizers, such as lithium or valproate.
Other names for this medication:
Aripiprazole,
Abilify,
Abilitat,
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